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When are idiopathic and clonal cytopenias of unknown significance (ICUS or CCUS)?特发性和克隆性血细胞减少症的不明意义（ICUS 或 CCUS）是什么时候？
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本文引用的文献

1
Myelodysplastic Syndromes, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.骨髓增生异常综合征，2.2017 年版，NCCN 肿瘤学临床实践指南。
J Natl Compr Canc Netw. 2017 Jan;15(1):60-87. doi: 10.6004/jnccn.2017.0007.
2
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.2016 年版世界卫生组织髓系肿瘤和急性白血病分类。
Blood. 2016 May 19;127(20):2391-405. doi: 10.1182/blood-2016-03-643544. Epub 2016 Apr 11.
3
MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance.MDS相关的体细胞突变和克隆性造血在意义未明的特发性血细胞减少症中很常见。
Blood. 2015 Nov 19;126(21):2355-61. doi: 10.1182/blood-2015-08-667063. Epub 2015 Oct 1.
4
Targeted sequencing identifies patients with preclinical MDS at high risk of disease progression.靶向测序可识别疾病进展风险高的临床前期 MDS 患者。
Blood. 2015 Nov 19;126(21):2362-5. doi: 10.1182/blood-2015-08-663237. Epub 2015 Sep 21.
5
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes.意义未明的克隆性造血及其与骨髓增生异常综合征的鉴别
Blood. 2015 Jul 2;126(1):9-16. doi: 10.1182/blood-2015-03-631747. Epub 2015 Apr 30.
6
Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis.白血病相关的体细胞突变驱动与年龄相关的克隆性造血的不同模式。
Cell Rep. 2015 Mar 3;10(8):1239-45. doi: 10.1016/j.celrep.2015.02.005. Epub 2015 Feb 26.
7
Age- and sex-related variations in platelet count in Italy: a proposal of reference ranges based on 40987 subjects' data.意大利血小板计数的年龄和性别相关变化：基于 40987 名受试者数据的参考范围建议。
PLoS One. 2013;8(1):e54289. doi: 10.1371/journal.pone.0054289. Epub 2013 Jan 31.
8
Revised international prognostic scoring system for myelodysplastic syndromes.修订版国际预后积分系统用于骨髓增生异常综合征。
Blood. 2012 Sep 20;120(12):2454-65. doi: 10.1182/blood-2012-03-420489. Epub 2012 Jun 27.
9
Idiopathic bone marrow dysplasia of unknown significance (IDUS): definition, pathogenesis, follow up, and prognosis.特发性骨髓发育不良，意义未明（IDUS）：定义、发病机制、随访和预后。
Am J Cancer Res. 2011;1(4):531-41. Epub 2010 Mar 16.
10
Idiopathic cytopenia of undetermined significance (ICUS) and idiopathic dysplasia of uncertain significance (IDUS), and their distinction from low risk MDS.特发性血细胞减少症的意义未明（ICUS）和特发性发育异常的意义未明（IDUS），及其与低危 MDS 的区别。
Leuk Res. 2012 Jan;36(1):1-5. doi: 10.1016/j.leukres.2011.08.016. Epub 2011 Sep 13.

Cytopenia levels for aiding establishment of the diagnosis of myelodysplastic syndromes.

作者信息

Greenberg Peter L, Tuechler Heinz, Schanz Julie, Sanz Guillermo, Garcia-Manero Guillermo, Solé Francesc, Bennett John M, Bowen David, Fenaux Pierre, Dreyfus Francois, Kantarjian Hagop, Kuendgen Andrea, Levis Alessandro, Malcovati Luca, Cazzola Mario, Cermak Jaroslav, Fonatsch Christa, Le Beau Michelle M, Slovak Marilyn L, Krieger Otto, Luebbert Michael, Maciejewski Jaroslaw, Magalhaes Silvia M M, Miyazaki Yasushi, Pfeilstöcker Michael, Sekeres Mikkael, Sperr Wolfgang R, Stauder Reinhard, Tauro Sudhir, Valent Peter, Vallespi Teresa, van de Loosdrecht Arjan A, Germing Ulrich, Haase Detlef

机构信息

Stanford University Cancer Institute, Stanford, CA.

Hanusch Hospital, Boltzmann Institute for Leukemia Research, Vienna, Austria.

出版信息

Blood. 2016 Oct 20;128(16):2096-2097. doi: 10.1182/blood-2016-07-728766. Epub 2016 Aug 17.

DOI:10.1182/blood-2016-07-728766
PMID:27535995
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5341483/
Abstract
摘要