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骨髓增生异常综合征,2.2017 年版,NCCN 肿瘤学临床实践指南。

Myelodysplastic Syndromes, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.

出版信息

J Natl Compr Canc Netw. 2017 Jan;15(1):60-87. doi: 10.6004/jnccn.2017.0007.

Abstract

The myelodysplastic syndromes (MDS) comprise a heterogenous group of myeloid disorders with a highly variable disease course. Diagnostic criteria to better stratify patients with MDS continue to evolve, based on morphology, cytogenetics, and the presence of cytopenias. More accurate classification of patients will allow for better treatment guidance. Treatment encompasses supportive care, treatment of anemia, low-intensity therapy, and high-intensity therapy. This portion of the guidelines focuses on diagnostic classification, molecular abnormalities, therapeutic options, and recommended treatment approaches.

摘要

骨髓增生异常综合征(MDS)是一组异质性髓系疾病,疾病过程变化较大。基于形态学、细胞遗传学和血细胞减少的存在,目前继续在发展更好地区分 MDS 患者的诊断标准。对患者进行更准确的分类将有助于更好的治疗指导。治疗包括支持性护理、贫血治疗、低强度治疗和高强度治疗。本指南的这一部分重点介绍诊断分类、分子异常、治疗选择和推荐的治疗方法。

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