Luu Cynthia A, Larson Ethan, Rankin Timothy M, Pappalardo Jennifer L, Slepian Marvin J, Armstrong David G
Southern Arizona Limb Salvage Alliance (SALSA), Department of Surgery, University of Arizona College of Medicine, Tucson, Ariz.; and Departments of Medicine and Biomedical Engineering, University of Arizona, Tucson Ariz.
Plast Reconstr Surg Glob Open. 2016 Jul 20;4(7):e810. doi: 10.1097/GOX.0000000000000813. eCollection 2016 Jul.
We report on the use of free fat grafting as a means of redistributing normal and shear stress after healing of plantar diabetic foot wounds. Although fat augmentation (lipofilling) has been described previously as an approach to supplement defects and prevent atrophy, including use as an adjunct to wound healing and to mitigate pain in the foot, we are unaware of any reports in the medical literature that have described its use in the high-risk diabetic foot in remission. An active 37-year-old man with type 2 diabetes and neuropathy presented with gangrene of his fifth ray, which was amputated. He subsequently developed a chronic styloid process ulceration that progressed despite treatment. We performed a tibialis anterior tendon transfer and total contact casting. He went on to heal but with residual fat pad atrophy and recalcitrant preulcerative lesions. We then used autologous fat grafting for the plantar atrophy. The patient was able to successfully transition to normal shoe gear after 4 weeks with successful engraftment without complication or recurrence of the wound at 6 weeks. This therapy may provide a promising adjunct to increase ulcer-free days to the patient in diabetic foot remission.
我们报告了在糖尿病足溃疡愈合后,使用游离脂肪移植作为重新分布正常应力和剪切应力的一种方法。尽管脂肪填充(脂肪移植)此前已被描述为一种补充缺损和预防萎缩的方法,包括作为伤口愈合的辅助手段以及减轻足部疼痛,但我们未在医学文献中发现任何关于其在缓解期高危糖尿病足中的应用报道。一名37岁的2型糖尿病且患有神经病变的男性患者,因第五跖骨坏疽接受了截肢手术。随后他出现了慢性茎突溃疡,尽管接受了治疗仍持续进展。我们进行了胫前肌腱转移和全接触石膏固定。他的伤口愈合了,但残留脂肪垫萎缩且有顽固性溃疡前期病变。然后我们对足底萎缩部位进行了自体脂肪移植。4周后患者能够成功过渡到正常鞋具,6周时移植成功,无并发症且伤口未复发。这种治疗方法可能为增加糖尿病足缓解期患者的无溃疡天数提供一种有前景的辅助手段。