• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

骨质疏松性髋部骨折后的非手术治疗策略

Nonsurgical Treatment Strategies after Osteoporotic Hip Fractures.

作者信息

Min Byung-Woo, Song Kwang-Soon, Bae Ki-Cheor, Cho Chul-Hyun, Son Eun-Suck, Lee Kyung-Jae

机构信息

Department of Orthopaedic Surgery, Keimyung University Dongsan Medical Center, Daegu, Korea.

出版信息

Hip Pelvis. 2015 Mar;27(1):9-16. doi: 10.5371/hp.2015.27.1.9. Epub 2015 Mar 31.

DOI:10.5371/hp.2015.27.1.9
PMID:27536596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4972623/
Abstract

Osteoporosis is a metabolic disease that is increasing in prevalence as people live longer. Because the orthopedic surgeon is frequently the first and often the only physician to manage patients with osteoporotic hip fractures, every effort should be made to prevent future fractures. A multidisciplinary approach is essential in treatment of osteoporotic fractures. Basic treatment includes calcium and vitamin D supplementation, fall prevention, hip protection, and balance and exercise programs. Currently available pharmacologic agents are divided into antiresorptive and anabolic groups. Antiresorptive agents such as bisphosphonates limit bone resorption through inhibition of osteoclastic activity. Anabolic agents such as parathyroid hormone promote bone formation.

摘要

骨质疏松症是一种随着人们寿命延长而患病率不断上升的代谢性疾病。由于骨科医生常常是首位且往往是唯一负责治疗骨质疏松性髋部骨折患者的医生，所以应尽一切努力预防未来的骨折。多学科方法对于骨质疏松性骨折的治疗至关重要。基本治疗包括补充钙和维生素D、预防跌倒、髋部保护以及平衡和运动计划。目前可用的药物分为抗吸收和促合成两类。双膦酸盐等抗吸收药物通过抑制破骨细胞活性来限制骨吸收。甲状旁腺激素等促合成药物则促进骨形成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5315/4972623/638f4061a723/hp-27-9-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5315/4972623/2a22737ecdfc/hp-27-9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5315/4972623/0268be40201c/hp-27-9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5315/4972623/a2042b705a31/hp-27-9-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5315/4972623/638f4061a723/hp-27-9-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5315/4972623/2a22737ecdfc/hp-27-9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5315/4972623/0268be40201c/hp-27-9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5315/4972623/a2042b705a31/hp-27-9-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5315/4972623/638f4061a723/hp-27-9-g004.jpg

相似文献

1
Nonsurgical Treatment Strategies after Osteoporotic Hip Fractures.骨质疏松性髋部骨折后的非手术治疗策略
Hip Pelvis. 2015 Mar;27(1):9-16. doi: 10.5371/hp.2015.27.1.9. Epub 2015 Mar 31.
2
Management of osteoporosis in the elderly.老年人骨质疏松症的管理
Curr Med Res Opin. 2009 Oct;25(10):2373-87. doi: 10.1185/03007990903169262.
3
Prevention of hip fractures: medical and nonmedical management.髋部骨折的预防：医学及非医学管理
Instr Course Lect. 2004;53:417-25.
4
Management of postmenopausal osteoporosis and the prevention of fractures.绝经后骨质疏松症的管理及骨折预防
Panminerva Med. 2014 Jun;56(2):115-31. Epub 2014 Jun 19.
5
Effect of osteoporosis medications on fracture healing.骨质疏松症药物对骨折愈合的影响。
Osteoporos Int. 2016 Mar;27(3):861-871. doi: 10.1007/s00198-015-3331-7. Epub 2015 Sep 29.
6
[Treatment of osteoporosis].[骨质疏松症的治疗]
Arh Hig Rada Toksikol. 2007 Mar;58(1):55-71. doi: 10.2478/v10004-007-0009-3.
7
Recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis: 2001 update. American College of Rheumatology Ad Hoc Committee on Glucocorticoid-Induced Osteoporosis.糖皮质激素性骨质疏松症的预防和治疗建议：2001年更新版。美国风湿病学会糖皮质激素性骨质疏松症特别委员会
Arthritis Rheum. 2001 Jul;44(7):1496-503. doi: 10.1002/1529-0131(200107)44:7<1496::AID-ART271>3.0.CO;2-5.
8
Glucocorticosteroid-induced spinal osteoporosis: scientific update on pathophysiology and treatment.糖皮质激素诱导的脊柱骨质疏松症：病理生理学与治疗的科学进展
Eur Spine J. 2006 Jul;15(7):1035-49. doi: 10.1007/s00586-005-0056-x.
9
[Update on treatment of postmenopausal osteoporosis].[绝经后骨质疏松症的治疗进展]
Rev Med Brux. 2008 Sep;29(4):301-9.
10
Patients with hip fracture: what can be improved?
Bone. 2006 Feb;38(2 Suppl 2):S8-12. doi: 10.1016/j.bone.2005.11.014. Epub 2006 Jan 9.

引用本文的文献

1
Development and Clinical Application of Phosphorus-Containing Drugs.含磷药物的研发与临床应用
Med Drug Discov. 2020 Dec;8:100063. doi: 10.1016/j.medidd.2020.100063. Epub 2020 Aug 25.
2
Clinical Results of Complex Subtrochanteric Femoral Fractures with Long Cephalomedullary Hip Nail.使用加长型股骨近端髓内钉治疗复杂型股骨转子下骨折的临床结果
Hip Pelvis. 2017 Jun;29(2):113-119. doi: 10.5371/hp.2017.29.2.113. Epub 2017 Jun 2.

本文引用的文献

1
Incongruities in the AAOMS position paper: medication-related osteonecrosis of the jaw--2014 update.美国口腔颌面外科医师协会立场文件中的不一致之处：颌骨药物性骨坏死——2014年更新版
J Oral Maxillofac Surg. 2014 Dec;72(12):2381. doi: 10.1016/j.joms.2014.07.045. Epub 2014 Oct 12.
2
A comparison of adverse event and fracture efficacy data for strontium ranelate in regulatory documents and the publication record.雷奈酸锶在监管文件和发表记录中的不良事件及骨折疗效数据比较。
BMJ Open. 2014 Oct 7;4(10):e005787. doi: 10.1136/bmjopen-2014-005787.
3
Timing of the initiation of bisphosphonates after surgery for fracture healing: a systematic review and meta-analysis of randomized controlled trials.
骨折愈合手术后双膦酸盐起始使用的时机：一项随机对照试验的系统评价和荟萃分析
Osteoporos Int. 2015 Feb;26(2):431-41. doi: 10.1007/s00198-014-2903-2. Epub 2014 Sep 30.
4
Once-weekly teriparatide administration for 24 weeks in postmenopausal women with osteoporosis.骨质疏松症绝经后女性每周一次给予特立帕肽，持续24周。
Osteoporos Int. 2014 Sep;25(9):2321. doi: 10.1007/s00198-014-2721-6. Epub 2014 May 21.
5
Calcium supplement intake and risk of cardiovascular disease in women.女性钙补充剂的摄入量与心血管疾病风险
Osteoporos Int. 2014 Aug;25(8):2047-56. doi: 10.1007/s00198-014-2732-3. Epub 2014 May 7.
6
The effects of once-weekly teriparatide on hip structure and biomechanical properties assessed by CT.每周一次的特立帕肽对通过CT评估的髋部结构和生物力学特性的影响。
Osteoporos Int. 2014 Mar;25(3):1163-72. doi: 10.1007/s00198-013-2596-y. Epub 2013 Dec 18.
7
Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research.非典型股骨转子下和骨干骨折：美国骨与矿物质研究学会特别工作组的第二次报告
J Bone Miner Res. 2014 Jan;29(1):1-23. doi: 10.1002/jbmr.1998. Epub 2013 Oct 1.
8
Does early administration of bisphosphonate affect fracture healing in patients with intertrochanteric fractures?早期使用双膦酸盐会影响股骨转子间骨折患者的骨折愈合吗？
J Bone Joint Surg Br. 2012 Jul;94(7):956-60. doi: 10.1302/0301-620X.94B7.29079.
9
Persistence with intravenous zoledronate in elderly patients with osteoporosis.老年骨质疏松症患者静脉注射唑来膦酸的坚持情况。
Osteoporos Int. 2012 Sep;23(9):2329-33. doi: 10.1007/s00198-011-1881-x. Epub 2011 Dec 17.
10
Atypical femoral fractures during prolonged use of bisphosphonates: short-term responses to strontium ranelate and teriparatide.长期使用双膦酸盐类药物后发生的非典型股骨骨折：雷奈酸锶和特立帕肽的短期疗效。
J Clin Endocrinol Metab. 2011 Sep;96(9):2675-80. doi: 10.1210/jc.2011-0593. Epub 2011 Jul 13.