Gupta Shikha, Chaurasia Abadh K, Chawla Rohan, Kapoor Kulwant Singh, Mahalingam Karthikeyan, Swamy Deepa R, Gupta Viney
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
Graefes Arch Clin Exp Ophthalmol. 2016 Dec;254(12):2449-2454. doi: 10.1007/s00417-016-3469-9. Epub 2016 Aug 18.
To evaluate long-term success of the Ahmed glaucoma valve (AGV) for refractory glaucoma after vitreoretinal surgery with silicone oil insertion.
Prospective non-comparative evaluation of patients who underwent AGV insertion for management of post-vitreoretinal surgery glaucoma, post-silicone oil removal. Intraocular pressure (IOP), visual acuity, and glaucomatous neuropathy status were evaluated preoperatively and at multiple follow-up visits postoperatively. Success, using Kaplan-Meier analysis, was determined at the 12-month follow-up visit and at the last follow-up. Factors associated with failure were analysed.
Twenty-seven eyes of 27 patients with a mean age of 28.3 ± 15.2 years underwent a superior AGV implantation. The average follow-up after AGV implantation was 17.11 ± 8.36 months (range: 9-60 months). Kaplan-Meier survival analysis revealed a 62 % success at 12 months and 37 % at 5 years. A 48 % rate of complications was noted, 22 % of which were vision-threatening. Factors analysed, including patient age, interval between vitreoretinal surgery and silicone oil removal, interval between vitreoretinal surgery and AGV implantation, and phakic status, were not found to be associated with higher failure rates.
Long-term success of AGV implantation for glaucoma after vitreoretinal surgery with silicone oil insertion is better than that reported for trabeculectomy, though complication rates remain high.
评估在玻璃体视网膜手术联合硅油植入后,使用艾哈迈德青光眼阀(AGV)治疗难治性青光眼的长期成功率。
对接受AGV植入以治疗玻璃体视网膜手术后青光眼及硅油取出术后患者进行前瞻性非对照评估。术前及术后多次随访时评估眼压(IOP)、视力和青光眼性神经病变状态。采用Kaplan-Meier分析,在12个月随访及末次随访时确定成功率。分析与失败相关的因素。
27例平均年龄为28.3±15.2岁患者的27只眼接受了上方AGV植入。AGV植入后的平均随访时间为17.11±8.36个月(范围:9 - 60个月)。Kaplan-Meier生存分析显示,12个月时成功率为62%,5年时为37%。并发症发生率为48%,其中22%对视力有威胁。分析的因素包括患者年龄、玻璃体视网膜手术与硅油取出之间的间隔、玻璃体视网膜手术与AGV植入之间的间隔以及晶状体状态,均未发现与较高的失败率相关。
玻璃体视网膜手术联合硅油植入后青光眼患者AGV植入的长期成功率优于小梁切除术报道的成功率,尽管并发症发生率仍然很高。