Miller John B, Papakostas Thanos D, Vavvas Demetrios G
Harvard Medical School, Massachusetts Eye and Ear Infirmary , Boston, Massachusetts , USA.
Semin Ophthalmol. 2014 Sep-Nov;29(5-6):312-8. doi: 10.3109/08820538.2014.962181.
Intraocular silicone oil has several important indications in vitreoretinal surgery, particularly the repair of complicated retinal detachments. Emulsification is a clinically significant complication of using silicone oil tamponade. There are several factors that can promote or prevent silicone oil emulsification after retinal detachment repair, including protein surfactants, contaminants, and shear forces. However, the duration of tamponade remains the most significant one. After emulsification has occurred, keratopathy and glaucoma are the most common complications. However, recent work has shown that emulsification can also affect the retina, optic nerve, and even extraocular structures. Limiting the amount of time the silicone oil remains in the eye is the most important factor in reducing its complications.
眼内硅油在玻璃体视网膜手术中有几个重要的适应证,尤其是复杂视网膜脱离的修复。乳化是使用硅油填塞的一种具有临床意义的并发症。有几个因素可促进或预防视网膜脱离修复后硅油的乳化,包括蛋白质表面活性剂、污染物和剪切力。然而,填塞时间仍然是最重要的因素。乳化发生后,角膜病变和青光眼是最常见的并发症。然而,最近的研究表明,乳化也可影响视网膜、视神经,甚至眼外结构。限制硅油在眼内停留的时间是减少其并发症的最重要因素。