Yazdani Alireza, Li Xuejin, Em Karniadakis George
Division of Applied Mathematics, Brown University, Providence, Rhode Island 02912, USA.
Rheol Acta. 2016 Jun;55(6):433-449. doi: 10.1007/s00397-015-0869-4. Epub 2015 Sep 3.
Quantifying dynamic and rheological properties of suspensions of soft biological particles such as vesicles, capsules, and red blood cells (RBCs) is fundamentally important in computational biology and biomedical engineering. In this review, recent studies on dynamic and rheological behavior of soft biological cell suspensions by computer simulations are presented, considering both unbounded and confined shear flow. Furthermore, the hemodynamic and hemorheological characteristics of RBCs in diseases such as malaria and sickle cell anemia are highlighted.
量化诸如囊泡、胶囊和红细胞（RBCs）等软生物颗粒悬浮液的动态和流变特性在计算生物学和生物医学工程中具有根本重要性。在这篇综述中，介绍了通过计算机模拟对软生物细胞悬浮液动态和流变行为的最新研究，同时考虑了无界和受限剪切流。此外，还强调了疟疾和镰状细胞贫血等疾病中红细胞的血液动力学和血液流变学特征。
