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Med Clin North Am. 2016 Sep;100(5):1057-64. doi: 10.1016/j.mcna.2016.04.014.
Approximately 10% to 15% of patients who experience chronic gastroesophageal reflux disease have Barrett esophagus, which is associated with an increased risk of esophageal adenocarcinoma. If symptoms persist after 8 weeks of adhering to treatment and lifestyle modifications, or if alarm symptoms develop, patients should be referred for screening upper endoscopy. Those with evidence of Barrett esophagus with dysplasia should be monitored in an endoscopic surveillance program, and those with high-grade dysplasia should consider surgical treatment.
约 10%至 15%经历慢性胃食管反流病的患者患有巴雷特食管，这与食管腺癌风险增加相关。如果在坚持治疗和生活方式改变 8 周后症状仍然持续，或者出现警报症状，患者应转介进行上消化道内镜检查。那些有异型增生的巴雷特食管证据的患者应在内镜监测计划中进行监测，那些有高级别异型增生的患者应考虑手术治疗。
