World J Gastroenterol. 2010 Aug 14;16(30):3743-4. doi: 10.3748/wjg.v16.i30.3743.
About 10%-15% of patients with gastroesophageal reflux disease develop Barrett's esophagus. This is considered a premalignant condition because it can progress from metaplasia to high-grade dysplasia, and eventually to adenocarcinoma. Recently, major advances have been made in the endoscopic treatment of Barrett's esophagus, therefore limiting the role of surgery in the treatment of this disease.
约 10%-15%的胃食管反流病患者会发展为 Barrett 食管。这被认为是一种癌前病变，因为它可以从化生进展为高级别异型增生，最终发展为腺癌。最近，Barrett 食管的内镜治疗取得了重大进展，因此手术在该疾病的治疗中的作用受到限制。
