Miller J Z, Statland B E, Roger B, Suther C, Furst J L, Fineberg N S
Indiana Med. 1989 Jul;82(7):526-31.
To evaluate the impact of large scale population screening for elevated total cholesterol, a city-wide event was scheduled in Indianapolis during nine days in February 1987. Altogether, 29,954 individuals were screened, and more than 32% were found to be at moderate or high risk using the classification recommended by the National Institutes of Health at the time of the screening for heart disease on the basis of their total plasma cholesterol concentrations. Although larger numbers of females and whites volunteered to be screened, the screened population represented a broad range of age and education levels. Results of a followup questionnaire returned by 18% of those at moderate of high risk revealed that after receipt of an elevated cholesterol result, 67% of the respondents scheduled a physician visit. The majority of those not doing so (53%) contacted their physician for other reasons or by telephone. Results of the followup indicate that screened subjects responded appropriately to the results received. The results of this project indicate that mass screening is only one tool to successfully identify individuals at risk. Given the biases present in the screened population, other strategies should be used to identify at-risk members of population groups unlikely to participate in similar screening events.
为评估大规模人群总胆固醇升高筛查的影响，1987年2月在印第安纳波利斯市安排了一场为期九天的全市范围活动。总共对29954人进行了筛查，根据筛查时美国国立卫生研究院推荐的基于血浆总胆固醇浓度对心脏病的分类标准，发现超过32%的人处于中度或高风险。尽管有更多女性和白人自愿接受筛查，但接受筛查的人群涵盖了广泛的年龄和教育水平。对18%的中度或高风险人群返回的后续调查问卷结果显示，在收到胆固醇升高的结果后，67%的受访者安排了看医生。大多数未这样做的人（53%）因其他原因或通过电话联系了他们的医生。后续结果表明，接受筛查的受试者对收到的结果做出了适当反应。该项目的结果表明，大规模筛查只是成功识别风险个体的一种工具。鉴于接受筛查人群中存在的偏差，应采用其他策略来识别不太可能参加类似筛查活动的人群中的风险成员。
