Fischer P M, Guinan K H, Burke J J, Karp W B, Richards J W
Department of Family Medicine, Medical College of Georgia, Augusta 30912.
Arch Intern Med. 1990 Dec;150(12):2567-72.
The National Cholesterol Education Program (NCEP) has endorsed physician case finding as the primary method to detect individuals with elevated cholesterol levels. Despite this recommendation, promotional and for-profit public screening programs have flourished. We surveyed participants of a mall-based cholesterol screening program 1 year after their screening. Sixty-four percent of those screened had not previously known their cholesterol levels. Those who were newly screened were less likely to benefit from this testing than the general public, since they were older (mean age, 55.3 years), more likely to be female (67.4%), and nonsmokers (88%). Screenees had excellent recall of their cholesterol level (mean absolute reporting error, 0.24 mmol/L [9 mg/dL]) and a good understanding of cholesterol as a coronary heart disease risk. Those with elevated cholesterol levels reported high distress from screening but no reduction in overall psychosocial well-being and an actual decrease in absenteeism. Only 53.7% of all who were advised to seek follow-up because of an elevated screening value had done so within the year following the screening program. However, of those with values greater than 6.2 mmol/L (240 mg/dL), 68% had sought follow-up. Many of those who participate in public screening programs have been previously tested, fall into low-benefit groups, or fail to comply with recommended follow-up. We therefore conclude that cholesterol screening programs of the type now commonly offered are unlikely to contribute greatly to the national efforts to further reduce coronary heart disease.
美国国家胆固醇教育计划(NCEP)认可医生病例筛查是检测胆固醇水平升高个体的主要方法。尽管有此建议,但商业性和盈利性的公共筛查项目仍蓬勃发展。我们对参加商场胆固醇筛查项目一年后的参与者进行了调查。64%接受筛查的人此前并不知道自己的胆固醇水平。新接受筛查的人从这项检测中获益的可能性低于普通公众,因为他们年龄更大(平均年龄55.3岁),女性比例更高(67.4%),且不吸烟(88%)。受检者对自己的胆固醇水平记忆良好(平均绝对报告误差为0.24 mmol/L[9 mg/dL]),并且对胆固醇作为冠心病风险因素有较好的理解。胆固醇水平升高的受检者表示筛查带来了高度困扰,但总体心理社会幸福感并未降低,旷工率反而实际下降。在因筛查值升高而被建议进行后续检查的所有人中,只有53.7%在筛查项目后的一年内进行了后续检查。然而,在那些筛查值大于6.2 mmol/L(240 mg/dL)的人中,68%进行了后续检查。许多参加公共筛查项目的人此前已经接受过检测,属于低受益群体,或者未遵守建议的后续检查要求。因此,我们得出结论,目前普遍开展的这类胆固醇筛查项目不太可能对国家进一步降低冠心病的努力做出重大贡献。