Department of Anaesthesiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Department of Vascular Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Br J Anaesth. 2016 Sep;117(3):316-23. doi: 10.1093/bja/aew268.
Patients undergoing carotid endarterectomy require strict arterial blood pressure (BP) control to maintain adequate cerebral perfusion. In this study we tested whether non-invasive beat-to-beat Nexfin finger BP (BPfin) can replace invasive beat-to-beat radial artery BP (BPrad) in this setting.
In 25 consecutive patients (median age 71 yr) scheduled for carotid endarterectomy and receiving general anaesthesia, BPfin and BPrad were monitored simultaneously and ipsilaterally during the 30-min period surrounding carotid artery cross-clamping. Validation was guided by the standard set by the Association for the Advancement of Medical Instrumentation (AAMI), which considers a BP monitor adequate when bias (precision) is <5 (8) mm Hg, respectively.
BPfin vs BPrad bias (precision) was -3.3 (10.8), 6.1 (5.7) and 3.5 (5.2) mm Hg for systolic, diastolic, and mean BP, respectively. One subject was excluded due to a poor quality BP curve. In another subject, mean BPfin overestimated mean BPrad by 13.5 mm Hg.
Mean BPfin could be considered as an alternative for mean BPrad during a carotid endarterectomy, based on the AAMI criteria. In 23 of 24 patients, the use of mean BPfin would not lead to decisions to adjust mean BPrad values outside the predefined BP threshold.
NCT01451294.
行颈动脉内膜切除术的患者需要严格控制动脉血压(BP)以维持足够的脑灌注。本研究旨在测试在这种情况下,非侵入性的 Nexfin 指套式血压(BPfin)是否可以替代有创的桡动脉血压(BPrad)。
在 25 例连续接受全身麻醉并拟行颈动脉内膜切除术的患者中,在颈动脉夹闭前后 30 分钟内,同步并同侧监测 BPfin 和 BPrad。验证方法遵循医疗器械促进协会(AAMI)的标准,当偏差(精度)分别小于 5(8)mmHg 时,认为血压监测仪是合格的。
BPfin 与 BPrad 的偏差(精度)分别为 -3.3(10.8)、6.1(5.7)和 3.5(5.2)mmHg,用于收缩压、舒张压和平均血压。1 名患者因血压曲线质量差而被排除。另有 1 名患者的平均 BPfin 高估了平均 BPrad 13.5mmHg。
根据 AAMI 标准,平均 BPfin 可作为颈动脉内膜切除术期间平均 BPrad 的替代方法。在 24 例患者中,有 23 例使用平均 BPfin 不会导致调整平均 BPrad 值超出预设的 BP 阈值。
临床试验.gov:NCT01451294。