Gaete Ximena, López Patricia, Unanue Nancy, Codner Ethel, Cavada Gabriel, Mericq Verónica
J Pediatr Endocrinol Metab. 2016 Sep 1;29(9):1063-7. doi: 10.1515/jpem-2016-0035.
Menarche is the last stage of pubertal development, which coincides, with the completion of longitudinal growth. Our aim was to evaluate, post-menarcheal growth and clinical variables proposed to be associated with this growth.
In a prospective fashion, 106 healthy girls attending five different socioeconomic status (SES) schools of Santiago were randomly recruited. A pediatric endocrinologist obtained anthropometrics and registration of date at menarche every 6 months. The evolution of the girls' heights was assessed through mixed models adjusted to the SESes, parental height and body mass index (BMI).
Sixty-three girls from a high socioeconomic status (HSS) and 50 from a low socioeconomic status (LSS) were followed. Four years post menarche, the girls reached a growth plateau and the average height gain was 5.2±2.5 cm. This gain was not associated with SES, BMI, nor with parental height (p=0.744). The only variable that modulated this gain was age at menarche (r=-0.1997, p=0.0332). There was an inverse correlation between height at the moment of menarche and the height reached after 4 years of follow-up adjusted to parental height (r=-0302, p=0.0011).
Post-menarcheal growth ends 4 years post-event and is inversely correlated with the age at menarche and with the height at the moment of menarche independent of BMI, parental height and SES.
月经初潮是青春期发育的最后阶段，与纵向生长的完成同时发生。我们的目的是评估月经初潮后的生长情况以及被认为与这种生长相关的临床变量。
以前瞻性方式，从圣地亚哥五所不同社会经济地位（SES）学校随机招募了106名健康女孩。一名儿科内分泌学家每6个月获取一次人体测量数据并记录月经初潮日期。通过根据社会经济地位、父母身高和体重指数（BMI）进行调整的混合模型评估女孩身高的变化情况。
对63名来自高社会经济地位（HSS）的女孩和50名来自低社会经济地位（LSS）的女孩进行了跟踪研究。月经初潮后四年，女孩们达到了生长平台期，平均身高增长为5.2±2.5厘米。这种增长与社会经济地位、BMI以及父母身高均无关（p = 0.744）。唯一调节这种增长的变量是月经初潮时的年龄（r = -0.1997，p = 0.0332）。月经初潮时的身高与随访4年后根据父母身高调整后的身高之间存在负相关（r = -0.302，p = 0.0011）。
月经初潮后的生长在月经初潮后4年结束，并且与月经初潮时的年龄以及月经初潮时的身高呈负相关，与BMI、父母身高和社会经济地位无关。
