Balaji Karunakaran, Subramanian Balaji, Yadav Poonam, Anu Radha Chandrasekaran, Ramasubramanian Velayudham
Department of Radiation Oncology, Global Hospitals, Chennai, India; School of Advanced Sciences, VIT University, Vellore, India.
Department of Radiation Oncology, Global Hospitals, Chennai, India.
Med Dosim. 2016 Autumn;41(3):253-7. doi: 10.1016/j.meddos.2016.06.005.
Concave shape with variable size target volume makes treatment planning for the breast/chest wall a challenge. Conventional techniques used for the breast/chest wall cancer treatment provided better sparing of organs at risk (OARs), with poor conformity and uniformity to the target volume. Advanced technologies such as intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) improve the target coverage at the cost of higher low dose volumes to OARs. Novel hybrid techniques present promising results in breast/chest wall irradiation in terms of target coverage as well as OARs sparing. Several published data compared these technologies for the benefit of the breast/chest wall with or without nodal volumes. The aim of this article is to review relevant data and identify the scope for further research in developing optimal treatment plan for breast/chest wall cancer treatment.
具有可变大小靶区体积的凹形使得乳腺/胸壁的治疗计划成为一项挑战。用于乳腺/胸壁癌治疗的传统技术能更好地保护危及器官（OARs），但对靶区体积的适形性和均匀性较差。诸如调强放射治疗（IMRT）和容积调强弧形治疗（VMAT）等先进技术在提高靶区覆盖率的同时，增加了危及器官的低剂量体积。新型混合技术在乳腺/胸壁照射的靶区覆盖率以及危及器官保护方面呈现出有前景的结果。一些已发表的数据比较了这些技术对有或无淋巴结体积的乳腺/胸壁的益处。本文的目的是回顾相关数据，并确定在制定乳腺/胸壁癌治疗的最佳治疗计划方面进一步研究的范围。
