非钙化性肥厚黄韧带导致严重颈椎管狭窄和脊髓病：病例报告及文献复习
Noncalcified Hypertrophic Ligamentum Flavum Causing Severe Cervical Stenosis and Myelopathy: Case Report and Review of the Literature.
作者信息
Coughlin Daniel J, Rymarczuk George N, Dirks Michael S
机构信息
Department of Neurosurgery, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
Department of Neurosurgery, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
出版信息
World Neurosurg. 2016 Nov;95:618.e21-618.e26. doi: 10.1016/j.wneu.2016.08.035. Epub 2016 Aug 18.
BACKGROUND
Calcified hypertrophic ligamentum flavum is a known entity that causes myeloradiculopathy of the cervical, thoracic, and lumbar spine and is seen more commonly in Asian populations. Noncalcified hypertrophic changes are less common and may mimic other epidural space-occupying lesions.
CASE DESCRIPTION
A 59-year-old woman presented with progressive myelopathy, and imaging studies were consistent with an epidural space-occupying lesion from C4-T3. The patient underwent posterior cervical decompression and fusion with instrumentation. Pathology specimens revealed noncalcified hypertrophic ligamentum flavum.
CONCLUSIONS
To our knowledge, noncalcified hypertrophic ligamentum flavum causing progressive cervical myelopathy has never been reported in the English literature. This entity should be considered in cases with epidural masses causing progressive myelopathy.
背景
钙化性肥厚性黄韧带是一种已知的可导致颈椎、胸椎和腰椎脊髓神经根病的病变，在亚洲人群中更为常见。非钙化性肥厚性改变较为少见，可能会模仿其他硬膜外占位性病变。
病例描述
一名59岁女性出现进行性脊髓病，影像学检查显示C4-T3水平有硬膜外占位性病变。患者接受了后路颈椎减压及器械辅助融合术。病理标本显示为非钙化性肥厚性黄韧带。
结论
据我们所知，英文文献中从未报道过非钙化性肥厚性黄韧带导致进行性颈椎脊髓病。对于出现导致进行性脊髓病的硬膜外肿块的病例，应考虑这一病变。
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