Jakó János, Szerafin László
Hematológiai Osztály, Szabolcs-Szatmár-Bereg Megyei Jósa András Oktatókórház Nyíregyháza.
Orv Hetil. 2016 Aug;157(34):1357-60. doi: 10.1556/650.2016.30490.
In their previous work, the authors reported findings from 30 years on the incidence of hematological malignancies in Szabolcs-Szatmár-Bereg county, Hungary. Until now there are no other studies on this topic available in Hungary.
Detailed analysis of epidemiologic features of patients with myeloma.
During a 33-year period (between January 1, 1983 and December 31, 2015) 4521 adult patients with hematologic malignancies were recorded in the leukaemia/lymphoma registry of Szabolcs-Szatmár-Bereg county. Among them 440 patients with myeloma (9.73%) were registered (397 multiple myeloma, 38 solitary, bone/soft tissue plasmocytoma, 5 primary plasma cell leukaemia).
The incidence of myeloma in Szabolcs-Szatmár-Bereg county showed an increasing tendency, with an overall incidence rate of 2.33/100 000 inhabitants/year. The male:female ratio was 45.9%:54.1%, the average age of patients was 65.1 (28-90) years, and 59.4% of the patients with multiple myeloma had IgG-type monoclonal immunoglobulin. There was no town or village in this county where the occurrence of patients with myeloma in one thousand inhabitants was significantly higher, than the average (0.78).
The epidemiologic features of myeloma in Szabolcs-Szatmár-Bereg county - except a moderate female dominance - is essentially similar to data published in the literature. Orv. Hetil., 2016, 157(34), 1357-1360.
在之前的研究中，作者报告了匈牙利绍博尔奇-萨特马尔-贝雷格县30年来血液系统恶性肿瘤发病率的研究结果。到目前为止，匈牙利尚无关于该主题的其他研究。
详细分析骨髓瘤患者的流行病学特征。
在33年期间（1983年1月1日至2015年12月31日），绍博尔奇-萨特马尔-贝雷格县白血病/淋巴瘤登记处记录了4521例成年血液系统恶性肿瘤患者。其中登记了440例骨髓瘤患者（9.73%）（397例多发性骨髓瘤，38例孤立性骨/软组织浆细胞瘤，5例原发性浆细胞白血病）。
绍博尔奇-萨特马尔-贝雷格县骨髓瘤的发病率呈上升趋势，总体发病率为2.33/10万居民/年。男女比例为45.9%:54.1%，患者平均年龄为65.1（28 - 90）岁，59.4%的多发性骨髓瘤患者具有IgG型单克隆免疫球蛋白。该县没有一个城镇或村庄的骨髓瘤患者发病率（每千名居民中）显著高于平均水平（0.78）。
绍博尔奇-萨特马尔-贝雷格县骨髓瘤的流行病学特征——除了女性占适度优势外——与文献中公布的数据基本相似。《匈牙利医学周报》，2016年，157(34)，1357 - 1360。
