Jakó János, Takács Péter, Szerafin László
Hematológiai Osztály,Szabolcs-Szatmár-Bereg Megyei Jósa András Oktatókórház, Nyíregyháza, Lukács Ödön u. 4., 4400.
Egészségügyi Kar, Egészségtudományi Intézet, Egészségügyi Informatikai Tanszék,Debreceni Egyetem, Nyíregyháza.
Orv Hetil. 2020 Aug;161(34):1400-1413. doi: 10.1556/650.2020.31750.
During a 36-year period (between January 1, 1983 and December 31, 2018), 5159 adult patients with newly diagnosed haematological malignancy were registered in the leukaemia/lymphoma registry of Szabolcs-Szatmár-Bereg county.
The review of the incidence of different haematological malignancy in the authors' county, and the changes of incidence from time to time, the associated haematological malignancies, and familial occurrence of malignant haematological diseases.
Detailed analysis of the data of the registry, with statistical analysis of incidence.
The incidence of Hodgkin disease and non-Hodgkin's lymphoma (1.49 and 7.12 new cases, respectively/100 000 inhabitants/year) was a little smaller, that of essential thrombocythaemia was larger than in the published data. The incidence of all other haematological malignancies corresponded to the data of the literature. The change of incidence of all malignant haematological diseases was similar to the published data. In the registry, there were 35 patients with two different malignant haematological diseases appearing simultaneously or successively. During the 36-year period, 88 families with haematological malignancies were recorded in the registry.
With the exception of Hodgkin disease, non-Hodgkin's lymphoma, and essential thrombocythaemia, the incidence of other haematological malignancies corresponded to the data of the literature. The change of incidence in all entities was similar to that observed by other authors. The authors in their country do not know other published data related to associated malignant haematological diseases. The observed anteposition in familial haematological diseases of uncle/aunt and nephew/cousin, and anteposition in malignant haematological diseases of siblings are equally new in the literature. Orv Hetil. 2020; 161(34): 1400-1413.
在1983年1月1日至2018年12月31日的36年期间，5159例新诊断的血液系统恶性肿瘤成年患者被登记在绍博尔奇-萨特马尔-贝赖格县的白血病/淋巴瘤登记处。
回顾作者所在县不同血液系统恶性肿瘤的发病率、发病率随时间的变化、相关的血液系统恶性肿瘤以及恶性血液病的家族发生情况。
对登记处的数据进行详细分析，并对发病率进行统计分析。
霍奇金病和非霍奇金淋巴瘤的发病率（分别为每年1.49例和7.12例新发病例/10万居民）略低于已发表的数据，原发性血小板增多症的发病率高于已发表的数据。所有其他血液系统恶性肿瘤的发病率与文献数据相符。所有恶性血液病发病率的变化与已发表的数据相似。在登记处，有35例患者同时或相继出现两种不同的恶性血液病。在这36年期间，登记处记录了88个有血液系统恶性肿瘤的家庭。
除霍奇金病、非霍奇金淋巴瘤和原发性血小板增多症外，其他血液系统恶性肿瘤的发病率与文献数据相符。所有实体发病率的变化与其他作者观察到的相似。作者所在国家不知道其他与相关恶性血液病有关的已发表数据。观察到的叔伯/姑姨与侄子/堂兄弟姐妹在家族性血液病中的顺位，以及兄弟姐妹在恶性血液病中的顺位在文献中同样是新的。《匈牙利医学周报》。2020年；161(34):1400 - 1413。
