Avcil Mucahit, Kapçı Mucahit, Yavaşoğlu Irfan, Kantekin Burçak, Akpek Mahmut
Department of Emergency Medicine, Adnan Menderes University Hospital, Aydın, Turkey.
Med Princ Pract. 2016;25(6):577-579. doi: 10.1159/000449250. Epub 2016 Aug 22.
The aim of this study was to highlight the use of combined intravenous lipid emulsion (ILE) and plasma exchange (PE) therapies in multidrug toxicity.
A 45-year-old woman who attempted suicide by ingesting large quantities of amisulpride (28 g), diazepam (250 mg), valsartan (2,240 mg), aripiprazole (45 mg) and paliperidone (21 mg) was taken to the hospital of Adnan Menderes University School of Medicine. Upon arrival, she exhibited signs of cardiotoxicity and severe depression of the central nervous and respiratory systems. She was treated successfully with ILE for 4 h and PE therapy for 36 h, consecutively. She was discharged on the fourth day of hospitalization having fully recovered.
The patient was successfully treated with the combination of ILE and PE.
本研究旨在强调静脉注射脂质乳剂（ILE）和血浆置换（PE）联合疗法在多药中毒中的应用。
一名45岁女性因大量服用氨磺必利（28克）、地西泮（250毫克）、缬沙坦（2240毫克）、阿立哌唑（45毫克）和帕利哌酮（21毫克）企图自杀，被送往阿德南·门德雷斯大学医学院附属医院。入院时，她表现出心脏毒性以及中枢神经系统和呼吸系统严重抑制的症状。她先后接受了4小时的ILE治疗和36小时的PE治疗，并取得成功。住院第四天，她已完全康复，顺利出院。
该患者通过ILE和PE联合治疗获得成功。
