Kalungia Aubrey Chichonyi, Burger Johanita, Godman Brian, Costa Juliana de Oliveira, Simuwelu Chimwemwe
a Department of Pharmacy , University of Zambia , Lusaka , Zambia.
b Medicine Usage in South Africa (MUSA), Faculty of Health Sciences , North-West University (Potchefstroom campus) , Potchefstroom , South Africa.
Expert Rev Anti Infect Ther. 2016 Dec;14(12):1215-1223. doi: 10.1080/14787210.2016.1227702. Epub 2016 Sep 9.
In Zambia, antibiotics are categorized as prescription-only medicines. Antibiotics dispensed without a prescription pose a public health threat, which is a concern. Consequently, the aim is to ascertain the extent of non-prescription sales and dispensing of antibiotics in community pharmacies in Zambia.
The practice of non-prescription sale and dispensing were assessed in 73 randomly selected community retail pharmacies, using a structured interviewer-administered questionnaire with simulated case scenarios.
Majority (97%) stated that clients frequently requested non-prescribed antibiotics. Interviewees usually asked clients' indications (94%), counselled on dosing (96%) and suggested changes to antibiotic choices (97%). All (100%) dispensed non-prescribed antibiotics. Commonly dispensed antibiotics included amoxicillin (52%), cotrimoxazole (25%) and metronidazole (23%). Non-prescription sale and dispensing of antibiotics was significantly associated with interviewees' professional qualification in four out of five simulations.
Non-prescription sale and dispensing of antibiotics is widespread in Zambia. Concerted public and professional interventions are needed coupled with stronger regulatory enforcement to reduce this.
在赞比亚,抗生素被归类为仅凭处方销售的药品。无处方配药的抗生素对公众健康构成威胁,这令人担忧。因此,目的是确定赞比亚社区药房非处方销售和配药抗生素的程度。
使用结构化的访谈者管理问卷和模拟病例场景,对73家随机选择的社区零售药房的非处方销售和配药情况进行评估。
大多数(97%)表示客户经常要求非处方抗生素。受访者通常会询问客户的症状(94%)、提供用药剂量建议(96%)并建议更改抗生素选择(97%)。所有(100%)都配了非处方抗生素。常用的抗生素包括阿莫西林(52%)、复方新诺明(25%)和甲硝唑(23%)。在五分之四的模拟中,抗生素的非处方销售和配药与受访者的专业资格显著相关。
抗生素的非处方销售和配药在赞比亚很普遍。需要公共和专业方面协同干预,并加强监管执法以减少这种情况。