Mudenda Steward, Chabalenge Billy, Daka Victor, Jere Elimas, Sefah Isaac, Wesangula Evelyn, Yamba Kaunda, Nyamupachitu Julian, Mugenyi Nathan, Mustafa Zia Ul, Mpundu Mirfin, Chizimu Joseph, Chilengi Roma
Department of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.
Department of Medicines Control, Zambia Medicines Regulatory Authority, Lusaka, Zambia.
JAC Antimicrob Resist. 2024 May 17;6(3):dlae076. doi: 10.1093/jacamr/dlae076. eCollection 2024 Jun.
Antimicrobial resistance (AMR) poses a threat to public health globally. Despite its consequences, there is little information about the knowledge, awareness, and practices towards AMR among healthcare workers (HCWs). Therefore, this study assessed the knowledge, awareness and practices regarding antimicrobial use (AMU), AMR and antimicrobial stewardship (AMS) among HCWs who are involved in the implementation of AMS activities across eight hospitals in Zambia.
A cross-sectional study was conducted among 64 HCWs from October to December 2023 using a semi-structured questionnaire. Data were analysed using IBM SPSS version 25.0.
Of the 64 HCWs, 59.4% were females, 60.9% were aged between 25 and 34 years, 37.5% were nurses, 18.7% were pharmacists, 17.2% were medical doctors and only one was a microbiologist. Overall, 75% of the HCWs had good knowledge, 84% were highly aware and 84% had good practices regarding AMU, AMR and AMS. Most of the HCWs (90.6%) responded that they had a multidisciplinary AMS team at their hospitals and were implementing the use of the WHO AWaRe classification of antibiotics.
This study found good knowledge levels, high awareness and good practices regarding AMU, AMR and AMS among HCWs who were involved in the implementation of AMS activities in hospitals in Zambia. Additionally, most hospitals have been conducting AMS training and implementing the use of the WHO AWaRe classification of antibiotics. However, there is still a need to address some identified gaps in AMU and AMR through the strengthening of AMS activities in hospitals.
抗菌药物耐药性（AMR）对全球公共卫生构成威胁。尽管有其后果，但关于医护人员（HCWs）对抗菌药物耐药性的知识、意识和做法的信息却很少。因此，本研究评估了参与赞比亚八家医院抗菌药物管理（AMS）活动实施的医护人员在抗菌药物使用（AMU）、抗菌药物耐药性和抗菌药物管理方面的知识、意识和做法。
2023年10月至12月，对64名医护人员进行了一项横断面研究，使用半结构化问卷。数据使用IBM SPSS 25.0版进行分析。
在64名医护人员中，59.4%为女性，60.9%年龄在25至34岁之间，37.5%为护士，18.7%为药剂师，17.2%为医生，只有一名是微生物学家。总体而言，75%的医护人员在抗菌药物使用、抗菌药物耐药性和抗菌药物管理方面有良好的知识，84%有高度的意识，84%有良好的做法。大多数医护人员（90.6%）回答说他们医院有一个多学科的抗菌药物管理团队，并正在实施世界卫生组织（WHO）的抗菌药物“获得、使用和合理使用”（AWaRe）分类。
本研究发现，参与赞比亚医院抗菌药物管理活动实施的医护人员在抗菌药物使用、抗菌药物耐药性和抗菌药物管理方面有良好的知识水平、高度的意识和良好的做法。此外，大多数医院一直在开展抗菌药物管理培训并实施世界卫生组织的抗菌药物“获得、使用和合理使用”分类。然而，仍有必要通过加强医院的抗菌药物管理活动来解决抗菌药物使用和抗菌药物耐药性方面一些已发现的差距。
