Schetz Daria, Waldman Wojciech, Sein Anand Jacek
Przegl Lek. 2016;73(8):593-95.
Recently we observe an increase in the number of intoxications due to xenobiotics that may induce acute methemoglobinemia. Our study showed a case of acute methemoglobinemia (MetHb 55..2%) in 25 – year old man. Clinical symptoms were caused by ingestion of “poppers” which was used by patient as “aphrodisiac”. Summary: Conclusions: 1. Oral intake of alkyl nitrites, including isobutyl nitrite, is burdened with the risk of life-threatening methemoglobinemia . 2. In the case of poisonings running with normal pO2, reduced level of oxygen saturation, clinical signs of cyanosis does not react to oxygen therapy, and “chocolate” tinge of blood methemoglobinemia should be suspected. 3. In every case of MetHb the use of antidote, which is methylene blue, should be considered. 4. The severity of cyanosis correlates with the level of methemoglobin.
最近，我们观察到因可能诱发急性高铁血红蛋白血症的外源性物质导致中毒的病例数量有所增加。我们的研究显示了一名25岁男性患急性高铁血红蛋白血症（高铁血红蛋白含量为55..2%）的病例。临床症状是由患者作为“壮阳药”服用的“Poppers”引起的。总结：结论：1. 口服亚硝酸烷基酯，包括亚硝酸异丁酯，存在危及生命的高铁血红蛋白血症风险。2. 在中毒时若pO2正常、氧饱和度降低、出现发绀的临床体征且对氧疗无反应，应怀疑高铁血红蛋白血症，血液呈“巧克力色”。3. 对于每一例高铁血红蛋白血症病例，都应考虑使用解毒剂亚甲蓝。4. 发绀的严重程度与高铁血红蛋白水平相关。
