• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Continuous spinal labor analgesia for two deliveries in a parturient with severe subvalvular aortic stenosis.

作者信息

Hyuga Shunsuke, Okutomi Toshiyuki, Kato Rie, Hosokawa Yuki

机构信息

Division of Obstetric Anesthesia, Center for Perinatal Care, Child Health and Development, Kitasato University Hospital, 1-15-1 Kitasato Minami-ku, Sagamihara City, Kanagawa, 252-0375, Japan.

出版信息

J Anesth. 2016 Dec;30(6):1067-1070. doi: 10.1007/s00540-016-2238-6. Epub 2016 Aug 22.

DOI:10.1007/s00540-016-2238-6
PMID:27549335
Abstract

Various degrees of left ventricular outflow tract (LVOT) obstruction have been seen in patients with subvalvular aortic stenosis (SAS). Regional analgesia during labor for parturients with SAS is relatively contraindicated because it has a potential risk for hemodynamic instability due to sympathetic blockade as a result of vasodilation by local anesthetics. We thought continuous spinal analgesia (CSA) using an opioid and minimal doses of local anesthetic could provide more stable hemodynamic status. We demonstrate the management of a 28-year-old pregnant patient with SAS who received CSA for her two deliveries. For her first delivery (peak pressure gradient (∆P) between LV and aorta was approximately 55 mmHg), intrathecal fentanyl was used as a basal infusion, but we needed a small amount of bupivacaine to provide supplemental intrathecal analgesia as labor progressed. Although there were mild fluctuations in hemodynamics, she was asymptomatic. For her second delivery (∆P between LV and aorta was approximately 90 mmHg), minimal doses of continuous bupivacaine were used as a basal infusion. For her additional analgesic requests, bolus co-administration of fentanyl was effective. There were no fluctuations in her hemodynamics. Although her SAS in her second pregnancy was more severe than in the first, her hemodynamics exhibited less fluctuation during the second delivery with this method. In conclusion, CSA using fentanyl combined with minimal doses of bupivacaine provided satisfactory analgesia and stable hemodynamics in parturient with severe SAS.

摘要

相似文献

1
Continuous spinal labor analgesia for two deliveries in a parturient with severe subvalvular aortic stenosis.
J Anesth. 2016 Dec;30(6):1067-1070. doi: 10.1007/s00540-016-2238-6. Epub 2016 Aug 22.
2
Patient-controlled epidural technique improves analgesia for labor but increases cesarean delivery rate compared with the intermittent bolus technique.与间断推注技术相比,患者自控硬膜外技术可改善分娩镇痛,但会增加剖宫产率。
Acta Anaesthesiol Scand. 2004 Jul;48(6):732-7. doi: 10.1111/j.0001-5172.2004.00413.x.
3
Combined spinal-epidural analgesia in the management of labouring parturients with mitral stenosis.联合脊髓-硬膜外镇痛用于二尖瓣狭窄产妇分娩的管理
Anaesth Intensive Care. 1999 Oct;27(5):523-6. doi: 10.1177/0310057X9902700516.
4
Intravenous dexamethasone as an adjunct to improve labor analgesia: A randomized, double-blinded, placebo controlled clinical trial.静脉内给予地塞米松作为辅助手段以改善分娩镇痛:一项随机、双盲、安慰剂对照临床试验。
J Clin Anesth. 2017 Dec;43:6-10. doi: 10.1016/j.jclinane.2017.09.003. Epub 2017 Sep 13.
5
Bupivacaine with meperidine versus bupivacaine with fentanyl for continuous epidural labor analgesia.
Saudi Med J. 2007 Jun;28(6):904-8.
6
Local anesthetics and mode of delivery: bupivacaine versus ropivacaine versus levobupivacaine.局部麻醉药与给药方式:布比卡因对比罗哌卡因对比左旋布比卡因
Anesth Analg. 2007 Sep;105(3):756-63. doi: 10.1213/01.ane.0000278131.73472.f4.
7
[Comparison of bupivacaine and levobupivacaine with epidural technique for labor analgesia].布比卡因与左旋布比卡因用于硬膜外分娩镇痛的比较
Agri. 2012;24(1):23-31. doi: 10.5505/agri.2012.82584.
8
Combined spinal-epidural analgesia and epidural analgesia in labor: effect of intrathecal fentanyl vs. epidural bupivacaine as a bolus.分娩时联合脊髓-硬膜外镇痛与硬膜外镇痛:鞘内注射芬太尼与硬膜外注射布比卡因推注的效果比较
J Med Assoc Thai. 2007 Jul;90(7):1368-74.
9
Subarachnoid analgesia in advanced labor: a comparison of subarachnoid analgesia and pudendal block in advanced labor: analgesic quality and obstetric outcome.晚期分娩中的蛛网膜下腔镇痛:晚期分娩中蛛网膜下腔镇痛与阴部神经阻滞的比较:镇痛质量与产科结局
Ann N Y Acad Sci. 2004 Dec;1034:356-63. doi: 10.1196/annals.1335.037.
10
Maternal and neonatal effects of adding morphine to low-dose bupivacaine for epidural labor analgesia.在低剂量布比卡因中添加吗啡用于硬膜外分娩镇痛的母婴效应。
Niger J Clin Pract. 2014 Mar-Apr;17(2):205-11. doi: 10.4103/1119-3077.127559.

引用本文的文献

1
Severe Subvalvular Aortic Stenosis in a Pregnant Woman.一名孕妇的重度瓣下主动脉狭窄
Heart Views. 2022 Jan-Mar;23(1):60-66. doi: 10.4103/heartviews.heartviews_26_22. Epub 2022 May 16.

本文引用的文献

1
Practical assessment of maternal cardiovascular risk in pregnancy.孕期母亲心血管风险的实际评估
Congenit Heart Dis. 2008 Sep-Oct;3(5):308-16. doi: 10.1111/j.1747-0803.2008.00207.x.
2
Post-dural puncture headache in young adults: comparison of two small-gauge spinal catheters with different needle design.年轻成年人的硬膜穿刺后头痛:两种不同针设计的小口径脊髓导管的比较
Br J Anaesth. 2005 May;94(5):657-61. doi: 10.1093/bja/aei100. Epub 2005 Feb 18.
3
Continuous spinal analgesia for labor pain in a parturient with aortic stenosis.
主动脉瓣狭窄产妇分娩镇痛的连续脊髓镇痛
Int J Obstet Anesth. 2003 Jan;12(1):51-4. doi: 10.1016/s0959-289x(02)00163-2.
4
Obstetric epidural analgesia in aortic stenosis: a low-dose technique for labour and instrumental delivery.
Int J Obstet Anesth. 2001 Apr;10(2):129-34. doi: 10.1054/ijoa.2000.0720.
5
The effect of intrathecal epinephrine on epidural infused analgesics during labor.鞘内注射肾上腺素对分娩期间硬膜外注入镇痛剂的影响。
Reg Anesth Pain Med. 2003 Mar-Apr;28(2):108-12. doi: 10.1053/rapm.2003.50026.
6
Continuous spinal analgesia for labor and delivery in a parturient with hypertrophic obstructive cardiomyopathy.肥厚型梗阻性心肌病产妇分娩时的连续脊髓镇痛
Acta Anaesthesiol Scand. 2002 Mar;46(3):329-31. doi: 10.1034/j.1399-6576.2002.t01-1-460317.x.
7
Over-the-needle versus microcatheter-through-needle technique for continuous spinal anesthesia: a preliminary study.
Reg Anesth Pain Med. 1999 Sep-Oct;24(5):417-21. doi: 10.1016/s1098-7339(99)90007-x.
8
Comparison of three different doses of intrathecal fentanyl and sufentanil for labor analgesia.三种不同剂量鞘内注射芬太尼和舒芬太尼用于分娩镇痛的比较。
J Clin Anesth. 1998 Sep;10(6):488-93. doi: 10.1016/s0952-8180(98)00076-2.
9
Combined spinal and epidural anesthesia in a parturient with idiopathic hypertrophic subaortic stenosis.一名患有特发性肥厚性主动脉瓣下狭窄的产妇的腰麻-硬膜外联合麻醉
Anesthesiology. 1997 Jul;87(1):168-9. doi: 10.1097/00000542-199707000-00024.
10
The efficacy of intrathecal injection of sufentanil using a microspinal catheter for labor analgesia.使用微脊髓导管鞘内注射舒芬太尼用于分娩镇痛的疗效。
Acta Anaesthesiol Scand. 1996 Feb;40(2):210-5. doi: 10.1111/j.1399-6576.1996.tb04421.x.