二维斑点追踪超声心动图评估缺铁性贫血患者的左心房功能
Evaluation of left atrial function in patients with iron-deficiency anemia by two-dimensional speckle tracking echocardiography.
作者信息
Shen Jiaqi, Zhou Qiao, Liu Yue, Luo Runlan, Tan Bijun, Li Guangsen
机构信息
Department of Ultrasound, The Second Affiliated Hospital of Dalian Medical University, Dalian, 116027, China.
出版信息
Cardiovasc Ultrasound. 2016 Aug 23;14(1):34. doi: 10.1186/s12947-016-0078-z.
BACKGROUND
Iron-deficiency anemia (IDA) is a global health problem and a common medical condition that can be seen in everyday clinical practice. And two-dimensional speckle tracking echocardiography (2D-STE) has been reported very useful in evaluating left atrial (LA) function, as well as left ventricular (LV) function. The aim of our study is to evaluate the LA function in patients with IDA by 2D-STE.
METHODS
65 patients with IDA were selected. This group of patients was then divided into two groups according to the degree of hemoglobin: group B (Hb > 90 g/L) and group C (Hb60 ~ 90 g/L). Another 30 healthy people were also selected as control group A. Conventional echocardiography parameters, such as left atrial diameter (LAD), peak E and A of mitralis (E, A), E/A, end-diastolic thickness of ventricular septum (IVST d), end-diastolic thickness of LV posterior wall (PWTd) and left ventricular end-diastolic dimension (LVDd) were obtained from these three groups. Left atrial minimum volume (LAVmin), left atrial pre-atrial contraction volume (LAVp) and left atrial maximum volume (LAVmax) were measured by Simpson's rule, whereas left atrial active ejection fraction (LAAEF) and left atrial passive ejection fraction (LAPEF) were obtained from calculation. Two-dimensional images were acquired from apical four-chamber view and two-chamber view to store images for offline analysis. The global peak atrial longitudinal strain and strain rate of systolic LV (GLSs, GLSRs) as well as early and late diastolic LV strain rate (GLSRe, GLSRa) curves of LA were acquired in each LA segment from basal segment to top segment of LA by 2D-STE.
RESULTS
Compared with group A, there were no differences between group B and group A (all P > 0.05). The LAAEF and GLSRa were significantly higher in group C compared with those of group A and group B (all P < 0.01). The LAPEF, GLSs, GLSRs and GLSRe were significantly lower in group C compared with those of group A and group B (all P < 0.01).
CONCLUSIONS
2D-STE could evaluate the LA function in patients with IDA.
背景
缺铁性贫血（IDA）是一个全球性的健康问题，也是日常临床实践中常见的病症。二维斑点追踪超声心动图（2D-STE）已被报道在评估左心房（LA）功能以及左心室（LV）功能方面非常有用。我们研究的目的是通过2D-STE评估IDA患者的LA功能。
方法
选取65例IDA患者。然后根据血红蛋白水平将这组患者分为两组：B组（Hb > 90 g/L）和C组（Hb 60 ~ 90 g/L）。另外选取30名健康人作为A组对照组。从这三组中获取常规超声心动图参数，如左心房直径（LAD）、二尖瓣E峰和A峰（E、A）、E/A、室间隔舒张末期厚度（IVST d）、左心室后壁舒张末期厚度（PWTd）和左心室舒张末期内径（LVDd）。采用Simpson法则测量左心房最小容积（LAVmin）、左心房房缩前容积（LAVp）和左心房最大容积（LAVmax），通过计算得出左心房主动射血分数（LAAEF）和左心房被动射血分数（LAPEF）。从心尖四腔心切面和两腔心切面获取二维图像以存储图像用于离线分析。通过2D-STE在LA从基底段到顶端段的每个LA节段获取LA的整体心房纵向峰值应变和收缩期左心室应变率（GLSs、GLSRs）以及舒张早期和晚期左心室应变率（GLSRe、GLSRa）曲线。
结果
与A组相比，B组与A组之间无差异（所有P > 0.05）。C组的LAAEF和GLSRa显著高于A组和B组（所有P < 0.01）。C组的LAPEF、GLSs、GLSRs和GLSRe显著低于A组和B组（所有P < 0.01）。
结论
2D-STE可评估IDA患者的LA功能。
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