Jin Yuan Zhe, Lee Jae Hyup
Department of Orthopedic Surgery, College of Medicine, Seoul National University, Seoul, Korea.
Department of Orthopedic Surgery, SMG-SNU Boramae Medical Center, Seoul, Korea.
J Korean Med Sci. 2016 Oct;31(10):1641-9. doi: 10.3346/jkms.2016.31.10.1641.
Brace is one of the most commonly used interventions to manage osteoporotic vertebral fracture. However, its authentic effectiveness remains unclear. The aim of this study was to investigate the efficacy of brace in patients with osteoporotic vertebral fractures. We conducted a literature review and meta-analysis following the guideline and handbook of the Cochrane collaboration. Ten published articles were included in this study and data from 4 randomized controlled trials were analyzed. Low quality evidence proved using Spinomed brace could bring large and significant beneficial effect to patients with sub-acute osteoporotic vertebral fractures. Very low quality evidence proved no significant difference between Spinomed orthosis, rigid brace and soft brace when they were used in patients with acute fractures. Therefore, it might be applicable to recommend middle term use of Spinomed orthosis to patients with subacute fracture. In addition, this study emphasized the need for high quality randomized controlled trials.
支具是治疗骨质疏松性椎体骨折最常用的干预措施之一。然而，其实际疗效仍不明确。本研究的目的是探讨支具治疗骨质疏松性椎体骨折患者的疗效。我们按照Cochrane协作网的指南和手册进行了文献综述和荟萃分析。本研究纳入了10篇已发表的文章，并分析了4项随机对照试验的数据。低质量证据表明，使用Spinomed支具可为亚急性骨质疏松性椎体骨折患者带来显著的有益效果。极低质量证据表明，Spinomed矫形器、硬支具和软支具在急性骨折患者中使用时无显著差异。因此，对于亚急性骨折患者，推荐中期使用Spinomed矫形器可能是适用的。此外，本研究强调了高质量随机对照试验的必要性。
