Smith Jared G, Knight Lucie, Stewart Amy, Smith Emma L, McCracken Lance M
Population Health Research Institute, St George's, University of London, London, UK.
INPUT Pain Management Unit, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Br J Pain. 2016 Feb;10(1):46-58. doi: 10.1177/2049463715601445. Epub 2015 Sep 23.
Observational studies using routinely collected data indicate that pain management programmes (PMPs) based on cognitive-behavioural principles are associated with clinically meaningful improvements for individuals with chronic pain. This study evaluated change across functional measures in a sample of chronic pain patients attending a 4-week residential PMP between 2006 and 2010. The findings were directly compared with published outcomes from an earlier period (1989-1998) at the same service.
Participants included 760 consecutive completers of a multidisciplinary PMP. Data were collected at pre-PMP, post-PMP (1-month post-discharge) and at a 9-month follow-up session. Group-based treatment effects and the reliability and clinical significance of change across functional measures were calculated and compared across cohorts.
Effect sizes for the recent cohort ranged from small to medium (.43-.67) for pain and physical functioning outcomes to large (.90-1.12) for psychological outcomes at post-treatment (n = 654), and from small (.30-.51) to medium (.58-.71) at 9-month follow-up (n = 493). Clinically significant gains on pain and psychological measures were achieved by 19-55% of patients at post-treatment and 17-44% at follow-up. Comparisons with the earlier cohort showed significantly stronger post-treatment outcomes but differences at follow-up were less marked.
These results add to the evidence base supporting the effectiveness of cognitive-behavioural therapy (CBT)-based pain management interventions. There were significantly larger gains in patient functioning in the recent dataset, suggesting improved programme delivery. But effects were less marked in the longer term, indicating a need for improvements in therapeutic models and related methods to promote meaningful and lasting changes.
利用常规收集的数据进行的观察性研究表明,基于认知行为原则的疼痛管理方案(PMPs)可使慢性疼痛患者在临床上获得有意义的改善。本研究评估了2006年至2010年间参加为期4周住院PMP的慢性疼痛患者样本在功能指标方面的变化。研究结果与同一机构早期(1989 - 1998年)公布的结果进行了直接比较。
参与者包括760名多学科PMP的连续完成者。在PMP前、PMP后(出院后1个月)和9个月随访时收集数据。计算基于组的治疗效果以及功能指标变化的可靠性和临床意义,并在各队列之间进行比较。
近期队列在治疗后(n = 654),疼痛和身体功能结果的效应量从小到中等(0.43 - 0.67),心理结果的效应量为大(0.90 - 1.12);在9个月随访时(n = 493),效应量从小(0.30 - 0.51)到中等(0.58 - 0.71)。19% - 55%的患者在治疗后在疼痛和心理指标上取得了具有临床意义的改善,随访时这一比例为17% - 44%。与早期队列的比较显示,治疗后的结果明显更强,但随访时的差异不太明显。
这些结果为支持基于认知行为疗法(CBT)的疼痛管理干预措施的有效性增加了证据。近期数据集中患者功能的改善明显更大,表明方案实施有所改进。但长期效果不太明显,这表明需要改进治疗模式和相关方法,以促进有意义和持久的变化。