Chabert Marie-Charlotte, Perrin Jeanne, Berbis Julie, Bretelle Florence, Adnot Sébastien, Courbiere Blandine
Département de médecine générale, Faculté de Médecine, Aix-Marseille Université, 27 Bd Jean Moulin 13385 Marseille, France.
Pôle Femmes-Mères-Enfants, AP-HM La Conception, Marseille, France; Aix Marseille Université, CNRS, IRD, Avignon Université, IMBE UMR 7263, 13397, Marseille, France; CECOS-Laboratoire de Biologie de la Reproduction, Pôle Femmes-Mères-Enfants, AP-HM La Conception, 147 Bd Baille, 13005 Marseille, France.
Eur J Obstet Gynecol Reprod Biol. 2016 Oct;205:15-20. doi: 10.1016/j.ejogrb.2016.07.504. Epub 2016 Aug 3.
The aim of this study was to evaluate the information pregnant women received regarding possible exposures to five recognized reprotoxic agents during their pregnancy.
A cohort study was conducted using two postnatal units in France. Women hospitalized in postnatal units were requested to complete a self-administered two part questionnaire. The first part gathered information about the patient's socio-professional level and the type of pregnancy follow-up. The second part examined the information the patient received regarding daily products containing the following known reprotoxic agents: bisphenol A, toluene, n-hexane, cis-chloroallyl-triaza-azonia-adamantane-chloride and O-phenyl-phenol. The women cited the sources of information. We combined the employment status and educational level to separate the women into two groups. The groups were then compared using the Chi Square test or Fisher's exact test.
RESULT(S): There were 390 women in this study. Our results showed the women received information regarding the following: 21.6% (n=84) regarding tin cans, 21.9% (n=85) concerning plastic meal boxes when heated in microwave ovens, 8.8% (n=32) about water in gas-bottles, 27.4% (n=106) about non-organic foods, 39.3% (n=152) about hair dyes, 17% (n=66) about nail polishes, 23.4% (n=103) about insect repellents, 34.4% (n=133) about "do-it-yourself" products, 2.1% (n=8) about gardening products, 26.7% (n=103) about electric plug-in repellents, 21.1% (n=81) about housekeeping products, and 6.8% (n=26) about register receipts. Women with a higher level of education and a qualified occupation were better informed about these daily products. These women were more likely to learn the information on their own (internet, media).
CONCLUSION(S): Our study showed French women did not receive sufficient information regarding potential exposures to reprotoxic agents during pregnancy.
本研究旨在评估孕妇在孕期所获得的关于可能接触五种已确认的生殖毒性物质的信息。
在法国利用两个产后护理单元开展了一项队列研究。要求在产后护理单元住院的女性填写一份自行填写的两部分问卷。第一部分收集有关患者社会职业水平和孕期随访类型的信息。第二部分调查患者所获得的关于含有以下已知生殖毒性物质的日常用品的信息：双酚A、甲苯、正己烷、顺式氯烯丙基三氮杂金刚烷氯化物和邻苯基苯酚。这些女性列举了信息来源。我们将就业状况和教育水平相结合，将女性分为两组。然后使用卡方检验或费舍尔精确检验对两组进行比较。
本研究中有390名女性。我们的结果显示，女性获得了以下方面的信息：21.6%（n = 84）关于锡罐，21.9%（n = 85）关于在微波炉中加热时的塑料饭盒，8.8%（n = 32）关于气瓶中的水，27.4%（n = 106）关于非有机食品，39.3%（n = 152）关于染发剂，17%（n = 66）关于指甲油，23.4%（n = 103）关于驱虫剂，34.4%（n = 133）关于“自己动手做”产品，2.1%（n = 8）关于园艺产品，26.7%（n = 103）关于电插式驱虫器，21.1%（n = 81）关于家居清洁产品，以及6.8%（n = 26）关于收银条。教育水平较高且职业合格的女性对这些日常用品了解得更多。这些女性更有可能通过自身（互联网、媒体）获取信息。
我们的研究表明，法国女性在孕期未获得关于潜在接触生殖毒性物质的充分信息。
