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升主动脉及半弓置换联合改良三分支支架型人工血管植入术治疗急性DeBakey Ⅰ型主动脉夹层

Ascending Aorta and Hemiarch Replacement Combined With Modified Triple-Branched Stent Graft Implantation for Repair of Acute DeBakey Type I Aortic Dissection.

作者信息

Chen Liang-Wan, Dai Xiao-Fu, Wu Xi-Jie, Liao Dong-Shan, Hu Yun-Nan, Zhang Hui, Dong Yi

机构信息

Department of Cardiac Surgery, Union Hospital, Fujian Medical University, Fuzhou, Fujian, China.

Department of Cardiac Surgery, Union Hospital, Fujian Medical University, Fuzhou, Fujian, China.

出版信息

Ann Thorac Surg. 2017 Feb;103(2):595-601. doi: 10.1016/j.athoracsur.2016.06.017. Epub 2016 Aug 20.

Abstract

BACKGROUND

To simplify extensive repair of acute DeBakey type I aortic dissection, ascending aorta and hemiarch replacement combined with modified triple-branched stent graft implantation was developed. The descriptions and early results of this technique are reported.

METHODS

From August 2014 to September 2015, 116 patients with acute DeBakey type I aortic dissection underwent ascending aorta and hemiarch replacement combined with modified triple-branched stent graft implantation. Clinical data of all patients were retrospectively reviewed. Survivors were followed up prospectively by computed tomography angiography.

RESULTS

The cardiopulmonary bypass time was 131.5 ± 10.7 minutes, the aortic cross-clamp time was 50.0 ± 9.9 minutes, and the selective cerebral perfusion and lower body arrest time was 17.2 ± 2.2 minutes. The in-hospital mortality rate was 3.4%. Two patients were lost during follow-up. One patient died of a cerebrovascular accident 2 months after discharge, and another died of chronic renal failure 5 months after discharge. At the 3-month postoperative scans, complete thrombus formation of the false lumen around the implanted modified triple-branched stent graft occurred in all survivors, at the diaphragmatic level in 69.7% patients, and at the superior mesenteric arterial level in 8.3% patients.

CONCLUSIONS

Extensive thoracic aorta repair of acute type I aortic dissection can be performed simply by combining ascending aorta and hemiarch replacement with modified triple-branched stent graft implantation. This technique can reduce the risk and technical difficulty of extensive thoracic aorta repair to levels close to those seen with ascending aorta and hemiarch graft replacement with open distal anastomosis.

摘要

背景

为简化急性DeBakey I型主动脉夹层的广泛修复,开发了升主动脉和半弓置换联合改良三分支支架型人工血管植入术。本文报道了该技术的描述及早期结果。

方法

2014年8月至2015年9月,116例急性DeBakey I型主动脉夹层患者接受了升主动脉和半弓置换联合改良三分支支架型人工血管植入术。对所有患者的临床资料进行回顾性分析。对存活患者采用计算机断层扫描血管造影进行前瞻性随访。

结果

体外循环时间为131.5±10.7分钟,主动脉阻断时间为50.0±9.9分钟,选择性脑灌注及下半身停循环时间为17.2±2.2分钟。住院死亡率为3.4%。随访期间有2例患者失访。1例患者出院后2个月死于脑血管意外,另1例患者出院后5个月死于慢性肾衰竭。术后3个月扫描时,所有存活患者植入的改良三分支支架型人工血管周围假腔均完全形成血栓,在膈肌水平形成血栓的患者占69.7%,在肠系膜上动脉水平形成血栓的患者占8.3%。

结论

急性I型主动脉夹层的广泛胸主动脉修复可通过升主动脉和半弓置换联合改良三分支支架型人工血管植入术简单完成。该技术可将广泛胸主动脉修复的风险和技术难度降低至接近升主动脉和半弓人工血管置换并开放远端吻合术的水平。

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