Casamassima D, Palazzo M, Vizzarri F, Coppola R, Costagliola C, Corino C, Di Costanzo A
Department of Agricultural, Environmental and Food Sciences, University of Molise, Campobasso, Italy.
Department of Medicine and Health Sciences, Località tappino, University of Molise, Campobasso, Italy.
J Anim Physiol Anim Nutr (Berl). 2017 Oct;101(5):e175-e184. doi: 10.1111/jpn.12584. Epub 2016 Aug 24.
Effects of dietary supplementation of Laurus nobilis on selected biochemical parameters and plasma oxidative status in growing rabbits, fed with and without enriched-fat diet, integrated with and without dried bay leaves meal, were investigated. In the test, 120 New Zealand white 35-day-old male rabbits were divided into four homogeneous groups of 30 animals each. A negative control group (CON) received a feed that met the animal nutrient requirement; a positive control group (CG) receiving a supplement of 2.5% pig fat in feed; an experimental group (GA) feeding an integration of 2.5% pig fat and 1 g/kg of dried bay leaves (Laurus nobilis) in feed; an experimental group (CA) with dried bay leaves at the rate of 1 g/kg in feed. The dietary integration with dried bay leaves meal have resulted in a significant decrease in the blood lipid profile, glycemic profile and liver enzymes, with reduced levels of ALT and AST, glucose, total cholesterol, LDL cholesterol, triglycerides and increased HDL cholesterol. Plasma oxidative status markers have statistically improved with an increase in blood total phenols, SOD, ORAC, the FRAP and lipo-vitamin concentration, together with a significant reduction in ROMs and the MDA values. The results of present research underline that the dietary treatment with bay leaves meal, in the extend of 1 g/kg feed, confirms the lowering cholesterol activity and the epato-protective and ipo-glycemic effect in enrich-fat diet, controlling the oxidative status of plasma markers.
研究了在有或无高脂饮食以及有或无干月桂叶粉的情况下,日粮中添加月桂(Laurus nobilis)对生长兔某些生化参数和血浆氧化状态的影响。试验中,120只35日龄的新西兰雄性白兔被分为4组,每组30只。阴性对照组(CON)饲喂满足动物营养需求的饲料;阳性对照组(CG)在饲料中添加2.5%的猪脂肪;实验组(GA)在饲料中添加2.5%的猪脂肪和1 g/kg干月桂叶(Laurus nobilis);实验组(CA)在饲料中添加1 g/kg干月桂叶。日粮中添加干月桂叶粉可显著降低血脂、血糖水平和肝酶,降低谷丙转氨酶(ALT)和谷草转氨酶(AST)、葡萄糖、总胆固醇、低密度脂蛋白胆固醇、甘油三酯水平,并提高高密度脂蛋白胆固醇水平。血浆氧化状态标志物在统计学上有所改善,血液总酚、超氧化物歧化酶(SOD)、氧自由基吸收能力(ORAC)、铁还原抗氧化能力(FRAP)和脂溶性维生素浓度增加,同时活性氧物质(ROMs)和丙二醛(MDA)值显著降低。本研究结果强调,日粮中添加1 g/kg干月桂叶粉的处理方式,证实了其在高脂饮食中具有降低胆固醇活性、保肝和降血糖作用,并能控制血浆标志物的氧化状态。