Department of Animal Production, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt.
Agriculture Biochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt.
Trop Anim Health Prod. 2024 Oct 3;56(8):325. doi: 10.1007/s11250-024-04126-4.
The use of agricultural waste in animal production has gained global interest. An eight-week trial was conducted to investigate the impacts of adding ethanolic guava leaf extract (GLE) as a feed supplement on the growth, feed utilization, immune response, nutrient digestibility, redox regulation, and blood health of growing rabbits. Ninety weaned growing rabbits were randomly assigned to three groups. The first group was fed a basal diet (GLE0), while the other two groups were fed the control diet fortified with 15 mg (GLE15) or 20 mg (GLE20) of GLE per kg of diet for 8 weeks. The HPLC analysis of GLE exhibited the presence of gallic acid, ferulic acid, catechin, and caffeic acid in significant amounts. The results indicated that final body weight, daily body weight, daily feed intake and nutrient digestibility were significantly higher in the GLE-treated groups compared to the un-treated group (p < 0.05). Dietary supplementation of GLE significantly reduced lipid contents including triglycerides, total cholesterol, LDL, HDL, and VLDL (P < 0.05), with the most significant results observed when adding 20 mg/kg to the diet. AST and ALT levels as well as cortisol hormone in rabbits fed GLE were lower than those in the GLE0 group (P < 0.05). Immunoglobulins (IgG and IgA), antioxidant biomarkers (SOD and TAC) and T3 hormone were significantly improved by GLE supplementation (P < 0.001). Rabbits fed with GLE had lower levels of ROS and MDA compared to those in the GLE0 group (P < 0.001). Moreover, the hepatic and intestinal architectures were maintained in all rabbits fed diets with GLE. The results suggest that GLE supplementation (20 mg/kg diet) in fattening rabbit diets could efficiently improve growth, health status, blood physiology, antioxidant capacity and tissue histology.
利用农业废弃物在动物生产中引起了全球关注。进行了为期八周的试验，以研究添加乙醇番石榴叶提取物（GLE）作为饲料补充剂对生长兔的生长、饲料利用、免疫反应、养分消化率、氧化还原调节和血液健康的影响。将 90 只断奶生长兔随机分为三组。第一组饲喂基础日粮（GLE0），另外两组分别在基础日粮中添加 15mg（GLE15）或 20mg（GLE20）GLE/kg 日粮，饲养 8 周。GLE 的 HPLC 分析表明，其中含有大量的没食子酸、阿魏酸、儿茶素和咖啡酸。结果表明，与未处理组相比，GLE 处理组的末重、日增重、日采食量和养分消化率均显著提高（p<0.05）。日粮中添加 GLE 显著降低了甘油三酯、总胆固醇、LDL、HDL 和 VLDL 的含量（P<0.05），其中添加 20mg/kg 到日粮中效果最显著。GLE 喂养的兔子的 AST 和 ALT 水平以及皮质醇激素均低于 GLE0 组（P<0.05）。免疫球蛋白（IgG 和 IgA）、抗氧化生物标志物（SOD 和 TAC）和 T3 激素均因 GLE 补充而显著提高（P<0.001）。与 GLE0 组相比，GLE 喂养的兔子的 ROS 和 MDA 水平较低（P<0.001）。此外，所有饲喂 GLE 日粮的兔子的肝和肠结构都得到了维持。结果表明，在育肥兔日粮中添加 GLE（20mg/kg 日粮）可有效提高生长性能、健康状况、血液生理、抗氧化能力和组织组织学。
