Giménez-Muñoz A, Ara J R, Abad Díez J M, Campello Morer I, Pérez Trullén J M
Sección de Neurología, Hospital Royo Villanova, Zaragoza, España.
Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, España.
Neurologia (Engl Ed). 2018 May;33(4):224-232. doi: 10.1016/j.nrl.2016.06.013. Epub 2016 Aug 21.
Despite the impact of cerebrovascular disease (CVD) on global health, its morbidity and time trends in Spain are not precisely known.
The purpose of our study was to characterise the epidemiology and trends pertaining to stroke in Aragon over the period 1998-2010.
We conducted a retrospective, descriptive study using the data of the Spanish health system's Minimum Data Set and included all stroke patients admitted to acute care hospitals in Aragon between 1 January 1998 and 31 December 2010. We present data globally and broken down by stroke subtype, sex, and age group.
The number of cases increased by 13% whereas age- and sex-adjusted hospitalisation rates showed a significant decrease for all types of stroke (mean annual decrease of 1.6%). Men and women in younger age groups showed opposite trends in hospitalisation rates for ischaemic stroke. Case fatality rate at 28 days (17.9%) was higher in patients with intracerebral haemorrhage (35.8%) than in those with subarachnoid haemorrhage (26.2%) or ischaemic stroke (13%). CVD case fatality showed a mean annual decline of 2.8%, at the expense of the fatality rate of ischaemic stroke, and it was more pronounced in men than in women.
Understanding stroke epidemiology and trends at the regional level will help establish an efficient monitoring system and design appropriate strategies for health planning.
尽管脑血管疾病（CVD）对全球健康有影响，但其在西班牙的发病率和时间趋势尚不清楚。
我们研究的目的是描述1998 - 2010年期间阿拉贡地区中风的流行病学特征和趋势。
我们使用西班牙卫生系统最小数据集的数据进行了一项回顾性描述性研究，纳入了1998年1月1日至2010年12月31日期间在阿拉贡地区急性护理医院收治的所有中风患者。我们展示了总体数据，并按中风亚型、性别和年龄组进行了细分。
病例数增加了13%，而年龄和性别调整后的住院率在所有类型的中风中均显著下降（平均每年下降1.6%）。年轻年龄组的男性和女性在缺血性中风住院率上呈现相反趋势。脑出血患者的28天病死率（17.9%）高于蛛网膜下腔出血患者（26.2%）或缺血性中风患者（13%）。CVD病死率平均每年下降2.8%，以缺血性中风的病死率为代价，且男性比女性更为明显。
了解地区层面的中风流行病学特征和趋势将有助于建立有效的监测系统，并为卫生规划设计适当的策略。
