Mendelian randomization analysis demonstrates that low vitamin D is unlikely causative for pediatric asthma.
作者信息
Hysinger Erik B, Roizen Jeffrey D, Mentch Frank D, Vazquez Lyam, Connolly John J, Bradfield Jonathan P, Almoguera Berta, Sleiman Patrick M, Allen Julian L, Levine Michael A, Hakonarson Hakon
机构信息
Center for Applied Genomics, the Children's Hospital of Philadelphia, Philadelphia, Pa; Division of Pulmonary Medicine, the Children's Hospital of Philadelphia, Philadelphia, Pa.
Division of Endocrinology and Diabetes, the Children's Hospital of Philadelphia, Philadelphia, Pa.
出版信息
J Allergy Clin Immunol. 2016 Dec;138(6):1747-1749.e4. doi: 10.1016/j.jaci.2016.06.056. Epub 2016 Aug 20.
Abstract
摘要
相似文献
1
Mendelian randomization analysis demonstrates that low vitamin D is unlikely causative for pediatric asthma.
J Allergy Clin Immunol. 2016 Dec;138(6):1747-1749.e4. doi: 10.1016/j.jaci.2016.06.056. Epub 2016 Aug 20.
2
Mendelian Randomization Studies Do Not Support a Role for Vitamin D in Coronary Artery Disease.
Circ Cardiovasc Genet. 2016 Aug;9(4):349-56. doi: 10.1161/CIRCGENETICS.116.001396. Epub 2016 Jul 14.
3
Circulating Vitamin D Levels and Alzheimer's Disease: A Mendelian Randomization Study in the IGAP and UK Biobank.
J Alzheimers Dis. 2020;73(2):609-618. doi: 10.3233/JAD-190713.
4
Vitamin D and asthma: A Mendelian randomization study.
Ann Allergy Asthma Immunol. 2017 Jul;119(1):95-97.e1. doi: 10.1016/j.anai.2017.05.018.
5
Vitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study.
PLoS Med. 2017 May 9;14(5):e1002294. doi: 10.1371/journal.pmed.1002294. eCollection 2017 May.
6
Serum 25-Hydroxyvitamin D Concentrations and Major Depression: A Mendelian Randomization Study.
Nutrients. 2018 Dec 15;10(12):1987. doi: 10.3390/nu10121987.
7
Non-linear Mendelian randomization publications on vitamin D report spurious findings and require major correction.
Eur Heart J. 2024 Aug 3;45(29):2677-2678. doi: 10.1093/eurheartj/ehae264.
8
The genetics of vitamin D.
Bone. 2019 Sep;126:59-77. doi: 10.1016/j.bone.2018.10.006. Epub 2018 Oct 12.
9
Circulating serum vitamin D levels and total body bone mineral density: A Mendelian randomization study.
J Cell Mol Med. 2019 Mar;23(3):2268-2271. doi: 10.1111/jcmm.14153. Epub 2019 Jan 13.
10
Vitamin D and Cardiovascular Disease: An Updated Narrative Review.
Int J Mol Sci. 2021 Mar 12;22(6):2896. doi: 10.3390/ijms22062896.
引用本文的文献
1
Specific airway resistance according to early maternal vitamin D status during pregnancy in children aged 5 to 6 years old from the FEPED cohort (RESPIFEPED).
Eur J Pediatr. 2025 Feb 5;184(2):176. doi: 10.1007/s00431-024-05954-0.
2
High dose dietary vitamin D allocates surplus calories to muscle and growth instead of fat via modulation of myostatin and leptin signaling.
Res Sq. 2024 May 8:rs.3.rs-4202165. doi: 10.21203/rs.3.rs-4202165/v1.
3
Association of serum vitamin C levels with Asthma in adults: results of NHANES 2003-2006 and mendelian randomization study.
BMC Pulm Med. 2024 Jan 2;24(1):4. doi: 10.1186/s12890-023-02821-w.
4
Socioeconomic status and asthma: A bidirectional Mendelian randomization study.
World Allergy Organ J. 2023 Jun 15;16(6):100790. doi: 10.1016/j.waojou.2023.100790. eCollection 2023 Jun.
5
Causal risk factors for asthma in Mendelian randomization studies: A systematic review and meta-analysis.
Clin Transl Allergy. 2022 Nov;12(11):e12207. doi: 10.1002/clt2.12207.
6
Vitamin D and Multiple Health Outcomes: An Umbrella Review of Observational Studies, Randomized Controlled Trials, and Mendelian Randomization Studies.
Adv Nutr. 2022 Aug 1;13(4):1044-1062. doi: 10.1093/advances/nmab142.
7
Vitamin D Levels and Risk of Juvenile Idiopathic Arthritis: A Mendelian Randomization Study.
Arthritis Care Res (Hoboken). 2023 Mar;75(3):674-681. doi: 10.1002/acr.24815. Epub 2022 Nov 26.
8
Genetically predicted serum vitamin D and COVID-19: a Mendelian randomisation study.
BMJ Nutr Prev Health. 2021 May 4;4(1):213-225. doi: 10.1136/bmjnph-2021-000255. eCollection 2021.
9
Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study.
PLoS Med. 2021 Jun 1;18(6):e1003605. doi: 10.1371/journal.pmed.1003605. eCollection 2021 Jun.
10
Vitamin D and Immunity in Infants and Children.
Nutrients. 2020 Apr 27;12(5):1233. doi: 10.3390/nu12051233.
本文引用的文献
1
Vitamin D supplementation modulates the immune system and improves atopic dermatitis in children.
Int Arch Allergy Immunol. 2015;166(2):91-6. doi: 10.1159/000371350. Epub 2015 Mar 13.
2
Double-blind randomised placebo-controlled trial of bolus-dose vitamin D3 supplementation in adults with asthma (ViDiAs).
Thorax. 2015 May;70(5):451-7. doi: 10.1136/thoraxjnl-2014-206449. Epub 2015 Feb 27.
3
Vitamin D levels and status amongst asthmatic and non-asthmatic adolescents in Cyprus: a comparative cross-sectional study.
BMC Public Health. 2015 Jan 31;15:48. doi: 10.1186/s12889-015-1385-2.
4
Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial.
JAMA. 2014 May;311(20):2083-91. doi: 10.1001/jama.2014.5052.
5
Calculating statistical power in Mendelian randomization studies.
Int J Epidemiol. 2013 Oct;42(5):1497-501. doi: 10.1093/ije/dyt179.
6
Vitamin D serum levels and markers of asthma control in Italian children.
J Pediatr. 2011 Mar;158(3):437-41. doi: 10.1016/j.jpeds.2010.08.043. Epub 2010 Sep 26.
7
Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study.
J Allergy Clin Immunol. 2010 Jul;126(1):52-8.e5. doi: 10.1016/j.jaci.2010.03.043. Epub 2010 Jun 9.
8
Serum 25-hydroxyvitamin D levels among US children aged 1 to 11 years: do children need more vitamin D?
Pediatrics. 2009 Nov;124(5):1404-10. doi: 10.1542/peds.2008-2041.
9
Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007.
J Allergy Clin Immunol. 2007 Nov;120(5 Suppl):S94-138. doi: 10.1016/j.jaci.2007.09.043.
Zotero 插件