Machado Rui, Teixeira Gabriela, Oliveira Pedro, Loureiro Luís, Pereira Carlos, Almeida Rui
Hospital de Santo António - Centro Hospitalar do Porto, Porto, Portugal.
Instituto de Ciências Biomédicas Abel Salazar, Porto, Portugal.
Braz J Cardiovasc Surg. 2016 Apr;31(2):132-9. doi: 10.5935/1678-9741.20160037.
Endovascular aneurysm repair (EVAR) is the therapy of choice in high risk patients with abdominal aortic aneurysm. The good results described are leading to the broadening of clinical indications to younger patients. However, reintervention rates seem higher and even with successful treatment sometimes there is growth of the aneurysm sac and rupture, meaning a failure of the therapeutic goal. This study proposes to analyse the impact of age in patients' selection and post-EVAR results.
The clinical records of consecutive patients undergoing endovascular aneurysm repair, between 2001 and 2013, were retrospectively reviewed. Patients were divided according to age groups (<70, 70-80 and >80 years). Gender, body mass index, aneurysm anatomic features, neck characteristics, iliac morphology, surgical indication, endograft type, anesthesic risk classification, length of stay, reinterventions and mortality were analysed and compared.
The study included 171 patients, 161 (94.1%) men, and mean age 74.1±8.9 years. The age group under 70 had 32% of the patients. Only three characteristics were found different among age groups: 1) body mass index was higher in younger patients, with a considerable trend toward significance (P=0.06); 2) surgical indication, in the younger group, surgeon's and the patient's option were more proeminent (P<0.05); 3) erectile dysfunction was higher in elderly group (P<0.05). No other clinical and anatomical characteristics or final outcomes were found statisticaly different among age groups.
The absence of statistically differences in mortality and reinterventions among age groups suggests that age by itself is not a relevant factor in endovascular aneurysm repair. Indeed, the three characteristics different in younger (obesity, sexual function and patient's choice) favor endovascular aneurysm repair.
血管内动脉瘤修复术(EVAR)是高危腹主动脉瘤患者的首选治疗方法。所报道的良好效果促使临床适应症扩大至更年轻的患者。然而,再次干预率似乎更高,而且即使治疗成功,有时动脉瘤囊仍会生长并破裂,这意味着治疗目标的失败。本研究旨在分析年龄对患者选择及血管内动脉瘤修复术后结果的影响。
回顾性分析2001年至2013年间连续接受血管内动脉瘤修复术患者的临床记录。患者按年龄组(<70岁、70 - 80岁和>80岁)进行分组。分析并比较性别、体重指数、动脉瘤解剖特征、颈部特征、髂部形态、手术指征、血管内移植物类型、麻醉风险分级、住院时间、再次干预情况及死亡率。
该研究纳入171例患者,其中男性161例(94.1%),平均年龄74.1±8.9岁。70岁以下年龄组患者占32%。在各年龄组之间仅发现三个特征存在差异:1)年轻患者的体重指数较高,有显著的趋势(P = 0.06);2)手术指征方面,在较年轻组中,外科医生和患者的选择更为突出(P < 0.05);3)老年组勃起功能障碍发生率更高(P < 0.05)。在各年龄组之间未发现其他临床和解剖特征或最终结果存在统计学差异。
各年龄组之间在死亡率和再次干预方面不存在统计学差异,这表明年龄本身并非血管内动脉瘤修复的相关因素。实际上,较年轻组中不同的三个特征(肥胖、性功能和患者选择)有利于血管内动脉瘤修复。