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腹主动脉瘤开放修复术后的性功能障碍:一家四级中心的16年经验及文献综述

Sexual dysfunction after open abdominal aortic aneurysm repair: 16 years' experience in a quaternary center and literature review.

作者信息

Schmid Bruno Pagnin, Muce Marcelo Vezzi, Bocos Rodrigo Gonzalez, Menezes Fábio Hüsemann

机构信息

Universidade Estadual de Campinas - UNICAMP, Campinas, SP, Brasil.

Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brasil.

出版信息

J Vasc Bras. 2024 Feb 5;23:e20230135. doi: 10.1590/1677-5449.202301352. eCollection 2024.

Abstract

BACKGROUND

Open abdominal aortic aneurysm (AAA) repair can lead to sexual dysfunction (SD) in men.

OBJECTIVES

To determine the prevalence of SD following open AAA repair, explore whether surgical techniques for aortic reconstruction can have a differential impact on the occurrence of SD, and summarize current knowledge in this field.

METHODS

Retrospective review of 100 patients submitted to open AAA repair between 1995 and 2010 in a quaternary center. Sexual dysfunction was assessed according to questions from the modified International Index of Erectile Function (IIEF), considering the condition before surgical repair and 3 months after surgery. The chi-square test, Fisher's exact test, and Student's test were used for statistical analyses.

RESULTS

100 patients were included (mean age = 66.4 years old). Normal sexual activity, no sexual activity, erectile dysfunction, and retrograde ejaculation with preserved erectile function were found in 36%, 21%, 18%, and 24% of patients, respectively. The group of patients with no sexual activity was older (mean age = 72.3 years old 64.5 years old, p < 0.001). Erectile dysfunction prevalence was higher in patients submitted to an aorto-bifemoral bypass (p = 0.032). Retrograde ejaculation was more frequent in patients submitted to an aorto-aortic bypass (p = 0.007).

CONCLUSIONS

Sexual function is a frequent condition intimately associated with the aortic reconstruction technique. The literature review found contradictory results regarding whether the endovascular approach is protective compared with open repair, but clearly demonstrated the importance of techniques targeting preservation of the internal iliac artery and the superior hypogastric plexus.

摘要

背景

开放性腹主动脉瘤(AAA)修复术可导致男性性功能障碍(SD)。

目的

确定开放性AAA修复术后SD的患病率,探讨主动脉重建手术技术是否会对SD的发生产生不同影响,并总结该领域的现有知识。

方法

回顾性分析1995年至2010年在一家四级中心接受开放性AAA修复术的100例患者。根据改良的国际勃起功能指数(IIEF)的问题评估性功能障碍,考虑手术修复前和术后3个月的情况。采用卡方检验、Fisher精确检验和学生检验进行统计分析。

结果

纳入100例患者(平均年龄=66.4岁)。分别有36%、21%、18%和24%的患者性功能正常、无性生活、勃起功能障碍以及勃起功能保留但逆行射精。无性生活的患者组年龄更大(平均年龄=72.3岁对64.5岁,p<0.001)。接受主动脉-双股动脉旁路移植术的患者勃起功能障碍患病率更高(p=0.032)。接受主动脉-主动脉旁路移植术的患者逆行射精更频繁(p=0.007)。

结论

性功能障碍是与主动脉重建技术密切相关的常见情况。文献综述发现,关于血管内治疗方法与开放修复相比是否具有保护作用存在相互矛盾的结果,但明确表明了针对保留髂内动脉和上腹下丛的技术的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b75/10903787/74dc158097da/jvb-23-e20230135-g01.jpg

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