Zatulina N I, Lukova N B
Oftalmol Zh. 1989(2):87-8.
The paper analyses results of clinical examination of patients with initial open-angle glaucoma--44 eyes of patients under 44 years of age and 96 eyes of patients above 50--and those of morphologic studies of 16 biopsies of the drainage zone of the eyes obtained at sinusotrabeculectomy in young and elderly patients. A complex investigation of the initial stage of open-angle glaucoma has shown identical clinico-morphologic changes responsible for this form of the disease in patients at any age. This identity is manifested itself by similar hydro- and blood microcirculatory disturbances, changes in the anterior chamber angle structures differing only quantitatively in patients of various age. Some distinctive peculiarities in the course of open-angle glaucoma are also noted in persons of young age. Morphologic studies have revealed qualitative differences in glaucomatous patients of young age, such as specific structures of collagenous fibers peculiar to embryonic period.
本文分析了原发性开角型青光眼患者的临床检查结果——44岁以下患者的44只眼和50岁以上患者的96只眼，以及对年轻和老年患者在鼻窦小梁切除术时获取的16份眼引流区活检组织的形态学研究结果。对原发性开角型青光眼初期的综合研究表明，在任何年龄的患者中，导致这种疾病形式的临床形态学变化是相同的。这种一致性表现为相似的水和血液微循环障碍，前房角结构的变化在不同年龄患者中仅在数量上有所不同。在年轻患者中也注意到了开角型青光眼病程中的一些独特特点。形态学研究揭示了年轻青光眼患者的质性差异，如胚胎期特有的胶原纤维特殊结构。
