Brock Malcolm, Chung Tae Hwan, Gaddam Sathvika Reddy, Kathait Anjaneya Singh, Ober Cecily, Georgiades Christos
Department of Thoracic Surgery, Center for Sweat Disorders, Johns Hopkins University, Baltimore, USA.
Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, USA.
Cardiovasc Intervent Radiol. 2016 Dec;39(12):1785-1788. doi: 10.1007/s00270-016-1455-6. Epub 2016 Aug 24.
Postural orthostatic tachycardia syndrome is characterized by orthostatic intolerance. Orthostasis (or other mild physical stress) triggers a cascade of inappropriate tachycardia, lightheadedness, palpitations, and often fainting. The underlying defect is sympathetic dysregulation of the heart, which receives its sympathetic tone from the cervical and upper thoracic sympathetic ganglia. Primary hyperhidrosis is also thought to be the result of sympathetic dysregulation. We present the case of a patient treated with CT-guided, percutaneous T2 EtOH sympatholysis for craniofacial hyperhidrosis. The patient also suffered from postural orthostatic tachycardia syndrome for many years and was unresponsive to treatment. Immediately after sympatholysis, the patient experienced resolution of both craniofacial hyperhidrosis and postural orthostatic tachycardia syndrome.
体位性直立性心动过速综合征的特征是直立不耐受。直立（或其他轻度身体应激）引发一系列不适当的心动过速、头晕、心悸，且常伴有昏厥。潜在缺陷是心脏的交感神经调节异常，心脏的交感神经张力来自颈交感神经节和上胸交感神经节。原发性多汗症也被认为是交感神经调节异常的结果。我们报告一例因颅面部多汗症接受CT引导下经皮T2乙醇交感神经溶解术治疗的患者。该患者多年来还患有体位性直立性心动过速综合征，对治疗无反应。交感神经溶解术后，患者的颅面部多汗症和体位性直立性心动过速综合征立即得到缓解。
