De Sousa P A, Tye B J, Bruce K, Dand P, Russell G, Collins D M, Greenshields A, McDonald K, Bradburn H, Canham M A, Kunath T, Downie J M, Bateman M, Courtney A
Roslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UK; Centre for Clinical Brain Sciences, University of Edinburgh, UK; MRC Centre for Regenerative Medicine, University of Edinburgh, UK.
Roslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UK.
Stem Cell Res. 2016 Jul;17(1):36-41. doi: 10.1016/j.scr.2016.04.020. Epub 2016 May 6.
The human embryonic stem cell line RCe013-A (RC-9) was derived under quality assured compliance with UK regulation, European Union Directives and International guidance for tissue procurement, processing and storage according to Good Manufacturing Practice (GMP) standards. The cell line was derived from a failed to fertilise oocyte voluntarily donated as unsuitable and surplus to fertility requirements following informed consent. RCe013-A (RC-9) shows normal pluripotency marker expression and differentiation to the three germ layers in vitro and in vivo. It has a normal 46XY male karyotype and microsatellite PCR identity, HLA and blood group typing data are available.
人类胚胎干细胞系RCe013 - A（RC - 9）是在符合英国法规、欧盟指令以及国际组织关于组织采购、处理和储存的指导方针的质量保证下，按照良好生产规范（GMP）标准衍生而来的。该细胞系源自一个未受精的卵母细胞，该卵母细胞在获得知情同意后，因不适合且超出生育需求而被自愿捐赠。RCe013 - A（RC - 9）在体外和体内均显示出正常的多能性标志物表达以及向三个胚层的分化能力。它具有正常的46XY男性核型，并且有微卫星PCR身份鉴定，同时可获取HLA和血型分型数据。
