Kubena L F, Huff W E, Harvey R B, Phillips T D, Rottinghaus G E
USDA, Agricultural Research Service, College Station, Texas 77841.
Poult Sci. 1989 May;68(5):622-6. doi: 10.3382/ps.0680622.
Effects of feeding diets containing deoxynivalenol (DON)-contaminated wheat (16 mg DON/kg) and purified T-2 toxin at 4 mg/kg singly and in combination were characterized in male broiler chicks from 1 day to 3 wk of age. Total body weight gains and final body weights were significantly reduced by the DON/T-2 toxin combination but were not significantly affected by the toxins singly. The efficiency of feed utilization was reduced in chicks fed either of the diets containing DON-contaminated wheat. The incidence and severity of oral lesions induced by T-2 toxin was increased in the DON/T-2 toxin combination. Several parameters not altered by DON or T-2 toxin singly were significantly affected by the combination, indicating that the combination may pose a potentially greater problem to the poultry industry than either of the mycotoxins individually.
研究了在1日龄至3周龄雄性肉鸡中，单独或联合饲喂含有脱氧雪腐镰刀菌烯醇（DON，16毫克DON/千克）污染小麦和4毫克/千克纯化T-2毒素的日粮的影响。DON/T-2毒素组合显著降低了总体重增加和最终体重，但单独的毒素对其没有显著影响。饲喂含有DON污染小麦的任何一种日粮的雏鸡，饲料利用率均降低。DON/T-2毒素组合增加了由T-2毒素诱导的口腔病变的发生率和严重程度。几个单独不受DON或T-2毒素影响的参数受到组合的显著影响，这表明该组合对家禽业可能构成比任何一种霉菌毒素单独造成的潜在更大问题。
