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产后青少年使用依托孕烯释放型避孕植入剂:一项随机对照试验。

Etonogestrel-Releasing Contraceptive Implant for Postpartum Adolescents: A Randomized Controlled Trial.

作者信息

Bryant Amy G, Bauer Anna E, Stuart Gretchen S, Levi Erika E, Zerden Matthew L, Danvers Antoinette, Garrett Joanne M

机构信息

Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

出版信息

J Pediatr Adolesc Gynecol. 2017 Jun;30(3):389-394. doi: 10.1016/j.jpag.2016.08.003. Epub 2016 Aug 22.

DOI:10.1016/j.jpag.2016.08.003
PMID:27561981
Abstract

STUDY OBJECTIVE

To compare immediate postpartum insertion of the contraceptive implant to placement at the 6-week postpartum visit among adolescent and young women.

DESIGN

Non-blinded, randomized controlled trial.

SETTING AND PARTICIPANTS

Postpartum adolescents and young women ages 14-24 years who delivered at an academic tertiary care hospital serving rural and urban populations in North Carolina.

INTERVENTIONS

Placement of an etonogestrel-releasing contraceptive implant before leaving the hospital postpartum, or at the 4-6 week postpartum visit.

MAIN OUTCOME MEASURES

Contraceptive implant use at 12 months postpartum.

RESULTS

Ninety-six participants were randomized into the trial. Data regarding use at 12 months were available for 64 participants, 37 in the immediate group and 27 in the 6-week group. There was no difference in use at 12 months between the immediate group and the 6-week group (30 of 37, 81% vs 21 of 27, 78%; P = .75). At 3 months, the immediate group was more likely to have the implant in place (34 of 37, 92% vs 19 of 27, 70%; P = .02).

CONCLUSION

Placing the contraceptive implant in the immediate postpartum period results in a higher rate of use at 3 months postpartum and appears to have similar use rates at 12 months compared with 6-week postpartum placement. Providing contraceptive implants to adolescents before hospital discharge takes advantage of access to care, increases the likelihood of effective contraception in the early postpartum period, appears to have no adverse effects on breastfeeding, and might lead to increased utilization at 1 year postpartum.

摘要

研究目的

比较青少年及年轻女性产后立即植入避孕植入剂与产后6周就诊时植入的情况。

设计

非盲随机对照试验。

地点及参与者

在北卡罗来纳州一家为农村和城市人口服务的学术性三级护理医院分娩的14 - 24岁产后青少年及年轻女性。

干预措施

产后出院前或产后4 - 6周就诊时植入依托孕烯释放避孕植入剂。

主要观察指标

产后12个月时避孕植入剂的使用情况。

结果

96名参与者被随机纳入试验。64名参与者有产后12个月时的使用数据,其中立即植入组37人,6周植入组27人。立即植入组和6周植入组在产后12个月时的使用情况无差异(37人中30人,81% 对比27人中21人,78%;P = 0.75)。在3个月时,立即植入组更有可能植入了植入剂(37人中34人,92% 对比27人中19人,70%;P = 0.02)。

结论

产后立即植入避孕植入剂在产后3个月时的使用率更高,与产后6周植入相比,产后12个月时的使用率似乎相似。在出院前为青少年提供避孕植入剂利用了就医机会,增加了产后早期有效避孕的可能性,似乎对母乳喂养没有不良影响,并且可能会使产后1年的使用率提高。

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