Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana.
Department of Biostatistics, Indiana University School of Medicine, Indianapolis, Indiana.
J Womens Health (Larchmt). 2020 Jun;29(6):815-818. doi: 10.1089/jwh.2019.8122. Epub 2020 Jan 28.
Rapid repeat pregnancy (RRP) is common among adolescents and is associated with adverse maternal and infant outcomes. Despite evidence that use of long-acting forms of contraception before hospital discharge can help minimize RRP rates, barriers to placement existed within the state of Indiana. We sought to determine state-specific RRP and induced abortion rates for adolescents based on chosen postpartum contraception to inform policy change. We examined a retrospective cohort of 227 adolescents (ages 12-18 years) who gave birth in Indiana between 2010 and 2012. Demographics, postpartum contraception, and subsequent pregnancies or abortions after the sentinel delivery were obtained. Rates of RRP based on type of immediate postpartum contraception, etonogestrel (ENG) contraceptive implant, depo-medroxyprogesterone acetate (DMPA) injection, and short-acting methods were compared. Bivariate and logistic regression analyses were conducted. RRP rates were 3.7% for those with ENG contraceptive implant, 22.6% for those with DMPA, and 39.1% for those who choose short-acting methods ( = 0.01). Adolescents who did not choose an ENG contraceptive implant were significantly more likely to have an RRP (adjusted odds ratio [aOR] = 11.8, 95% confidence interval: 2.74-110.3), compared with other contraceptive methods, even after adjusting for covariates such as age, prior pregnancies, and postpartum visit attendance. Immediate postpartum receipt of ENG implant was significantly associated with a lower likelihood of RRP in adolescents in Indiana. These data facilitated state policy change regarding insurance reimbursement to improve statewide access for all women, regardless of age, showing how local data can inform policy change.
快速重复妊娠(RRP)在青少年中很常见,与母婴不良结局有关。尽管有证据表明,在出院前使用长效避孕形式可以帮助降低 RRP 率,但印第安纳州存在着避孕措施的实施障碍。我们旨在根据产后选择的避孕方法来确定青少年的特定州 RRP 和人工流产率,以告知政策的改变。我们研究了一个回顾性队列,其中包括 2010 年至 2012 年在印第安纳州分娩的 227 名青少年(年龄 12-18 岁)。获取了人口统计学、产后避孕以及分娩后再次怀孕或人工流产的信息。根据即时产后避孕方法、依托孕诺酮(ENG)避孕植入物、地诺孕素醋酸酯(DMPA)注射和短效方法的类型比较 RRP 的发生率。进行了单变量和逻辑回归分析。ENG 避孕植入物的 RRP 发生率为 3.7%,DMPA 为 22.6%,短效方法为 39.1%(P=0.01)。与其他避孕方法相比,选择 ENG 避孕植入物的青少年 RRP 发生率明显更低(调整后的优势比[aOR]为 11.8,95%置信区间:2.74-110.3),即使在调整了年龄、既往妊娠和产后就诊等协变量后也是如此。印第安纳州青少年产后即刻接受 ENG 植入物与 RRP 发生率降低显著相关。这些数据促成了州政策的改变,以改善全州范围内所有妇女的保险报销,无论年龄大小,展示了如何利用本地数据来推动政策的改变。