Yang Bo, Patel Himanshu J, Williams David M, Dasika Narasimham L, Deeb G Michael
University of Michigan Medical Center, Ann Arbor, Michigan, USA.
Ann Cardiothorac Surg. 2016 Jul;5(4):265-74. doi: 10.21037/acs.2016.07.04.
Malperfusion is a common lethal complication of acute aortic dissection following rupture, for which the optimal management strategy has yet to be clearly established. The objective of this study was to reassess the management of acute type A aortic dissection (Type A-AAD) with malperfusion. We retrospectively analyzed the outcomes of all patients with Type A-AAD with malperfusion at the University of Michigan and compared the results from patients that directly underwent open surgical repair versus those who had percutaneous reperfusion prior to open surgical repair. Based on the results, we developed a patient care protocol for the treatment of all patients with acute type A dissection. We later re-analyzed the long-term outcomes for patients using the protocol. The present study demonstrated that, although the outcomes for patients with acute type A aortic dissection with malperfusion syndrome treated with initial percutaneous reperfusion and delayed open surgical intervention are not as good as the results for patients with uncomplicated Type A-AAD that undergo immediate surgical repair, their outcomes continue the long-term outcomes of the former group are superior. To outdo patients with acute type A aortic dissection with malperfusion syndrome treated with immediate open surgical intervention. In conclusion, at the University of Michigan we continue to use our patient care protocol to treat patients with Type A-AAD.
灌注不良是急性主动脉夹层破裂后的一种常见致命并发症,其最佳治疗策略尚未明确确立。本研究的目的是重新评估伴有灌注不良的急性A型主动脉夹层(A型主动脉夹层)的治疗方法。我们回顾性分析了密歇根大学所有伴有灌注不良的A型主动脉夹层患者的治疗结果,并比较了直接接受开放手术修复的患者与在开放手术修复前接受经皮再灌注的患者的结果。基于这些结果,我们制定了针对所有急性A型夹层患者的患者护理方案。随后,我们使用该方案重新分析了患者的长期结果。本研究表明,虽然初始经皮再灌注和延迟开放手术干预治疗的伴有灌注不良综合征的急性A型主动脉夹层患者的结果不如直接接受手术修复的无并发症A型主动脉夹层患者,但他们的长期结果优于前者。为了超过直接接受开放手术干预治疗的伴有灌注不良综合征的急性A型主动脉夹层患者。总之,在密歇根大学,我们继续使用我们的患者护理方案来治疗A型主动脉夹层患者。