Marcove R C, Lindeque B G, Huvos A G
Department of Orthopedics, Memorial Sloan-Kettering Cancer Center, New York, New York.
Surg Gynecol Obstet. 1989 Aug;169(2):115-8.
Fourteen patients with fibromyxoma of the bone, a rare but relatively overlooked entity, are described. This tumor is different from a chondromyxoid fibroma in age distribution, clinical behavior and histologic appearance. Fibromyxoma occurs frequently in later life (after 50 years of age). It is usually not clinically aggressive and lacks the lobular pattern, chondroid matrix and cell variety of chondromyxoid fibroma. Secondary aneurysmal bone cysts developed in three patients. It behooves the pathologist to screen patients with aneurysmal bone cysts for evidence of pre-existing fibromyxoma, especially if the patient is less than 40 years of age. Treatment consists of curettage with or without cryosurgical procedures. Marginal excision may be necessary for an occasional aggressive lesion.
本文描述了14例骨纤维黏液瘤患者，这是一种罕见但相对被忽视的疾病。该肿瘤在年龄分布、临床行为和组织学表现上与软骨黏液样纤维瘤不同。纤维黏液瘤常见于晚年（50岁以后）。它通常在临床上不具侵袭性，且缺乏软骨黏液样纤维瘤的小叶状结构、软骨样基质和细胞多样性。3例患者出现了继发性动脉瘤样骨囊肿。病理学家有必要对患有动脉瘤样骨囊肿的患者进行筛查，以寻找先前存在的纤维黏液瘤的证据，特别是如果患者年龄小于40岁。治疗方法包括刮除术，可结合或不结合冷冻手术。对于偶尔出现的侵袭性病变，可能需要进行边缘切除。
