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乳腺钼靶筛查后被召回女性中手持超声与自动乳腺超声的比较

Comparison of handheld ultrasound and automated breast ultrasound in women recalled after mammography screening.

作者信息

Hellgren Roxanna, Dickman Paul, Leifland Karin, Saracco Ariel, Hall Per, Celebioglu Fuat

机构信息

1 Department of Medical Imaging, Division of Breast Imaging, Södersjukhuset, Stockholm, Sweden.

2 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

出版信息

Acta Radiol. 2017 May;58(5):515-520. doi: 10.1177/0284185116665421. Epub 2016 Sep 30.

Abstract

Background Automated breast volume scanner (ABVS) is an ultrasound (US) device with a wide scanner that sweeps over a large area of the breast and the acquired transverse images are sent to a workstation for reconstruction and review. Whether ABVS is as reliable as handheld US is, however, still not established. Purpose To compare the sensitivity and specificity of ABVS to handheld breast US for detection of breast cancer, in the situation of recall after mammography screening. Material and Methods A total of 113 women, five with bilateral suspicious findings, undergoing handheld breast US due to a suspicious mammographic finding in screening, underwent additional ABVS. The methods were assessed for each breast and each detected lesion separately and classified into two categories: breasts with mammographic suspicion of malignancy and breasts with a negative mammogram. Results Twenty-six cancers were found in 25 women. In the category of breasts with a suspicious mammographic finding (n = 118), the sensitivity of both handheld US and ABVS was 88% (22/25). The specificity of handheld US was 93.5% (87/93) and ABVS was 89.2% (83/93). In the category of breasts with a negative mammography (n = 103), the sensitivity of handheld US and ABVS was 100% (1/1). The specificity of handheld US was 100% (102/102) and ABVS was 94.1% (96/102). Conclusion ABVS can potentially replace handheld US in the investigation of women recalled from mammography screening due to a suspicious finding. Due to the small size of our study population, further investigation with larger study populations is necessary before the implementation of such practice.

摘要

背景

自动乳腺容积扫描仪(ABVS)是一种超声(US)设备,其具有宽幅扫描器,可扫过乳房的大片区域,获取的横向图像会发送到工作站进行重建和查看。然而,ABVS是否与手持超声一样可靠仍未确定。目的:在乳腺钼靶筛查后召回的情况下,比较ABVS与手持乳腺超声检测乳腺癌的敏感性和特异性。材料与方法:共有113名女性,其中5名有双侧可疑发现,因筛查中乳腺钼靶检查发现可疑而接受手持乳腺超声检查,之后又接受了ABVS检查。对每个乳房和每个检测到的病变分别评估方法,并分为两类:乳腺钼靶怀疑恶性的乳房和乳腺钼靶检查阴性的乳房。结果:在25名女性中发现了26例癌症。在乳腺钼靶检查有可疑发现的乳房类别(n = 118)中,手持超声和ABVS的敏感性均为88%(22/25)。手持超声的特异性为93.5%(87/93),ABVS为89.2%(83/93)。在乳腺钼靶检查阴性的乳房类别(n = 103)中,手持超声和ABVS的敏感性均为100%(1/1)。手持超声的特异性为100%(102/102),ABVS为94.1%(96/102)。结论:在对因可疑发现而从乳腺钼靶筛查中召回的女性进行检查时,ABVS有可能取代手持超声。由于我们的研究人群规模较小,在实施这种做法之前,有必要用更大的研究人群进行进一步调查。

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