Lin Han, Zhu Ping, Lin Qiuping, Huang Xiaoqiong, Xu Yue, Yang Xiaoping
Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, China.
Department of Orthodontics, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, China.
PLoS One. 2016 Aug 29;11(8):e0161601. doi: 10.1371/journal.pone.0161601. eCollection 2016.
Facial asymmetry often persists even after mandibular deviation corrected by the bilateral sagittal split ramus osteotomy (BSSRO) operation, since the reference facial sagittal plane for the asymmetry analysis is usually set up before the mandibular menton (Me) point correction. Our aim is to develop a predictive and quantitative method to assess the true asymmetry of the mandible after a midline correction performed by a virtual BSSRO, and to verify its availability by evaluation of the post-surgical improvement.
A retrospective cohort study was conducted at the Hospital of Stomatology, Sun Yat-sen University (China) of patients with pure hemi-mandibular elongation (HE) from September 2010 through May 2014. Mandibular models were reconstructed from CBCT images of patients with pre-surgical orthodontic treatment. After mandibular de-rotation and midline alignment with virtual BSSRO, the elongation hemi-mandible was virtually mirrored along the facial sagittal plane. The residual asymmetry, defined as the superimposition and boolean operation of the mirrored elongation side on the normal side, was calculated, including the volumetric differences and the length of transversal and vertical asymmetry discrepancy. For more specific evaluation, both sides of the hemi-mandible were divided into the symphysis and parasymphysis (SP), mandibular body (MB), and mandibular angle (MA) regions. Other clinical variables include deviation of Me point, dental midline and molar relationship. The measurement of volumetric discrepancy between the two sides of post-surgical hemi-mandible were also calculated to verify the availability of virtual surgery. Paired t-tests were computed and the P value was set at .05.
This study included 45 patients. The volume differences were 407.8±64.8 mm3, 2139.1±72.5 mm3, and 422.5±36.9 mm3; residual average transversal discrepancy, 1.9 mm, 1.0 mm, and 2.2 mm; average vertical discrepancy, 1.1 mm, 2.2 mm, and 2.2 mm (before virtual surgery). The post-surgical volumetric measurement showed no statistical differences between bilateral mandibular regions.
Mandibular asymmetry persists after Me point correction. A 3D quantification of mandibular residual asymmetry after Me point correction and mandible de-rotation with virtual BSSRO sets up a true reference mirror plane for comprehensive asymmetry assessment of bilateral mandibular structure, thereby providing an accurate guidance for orthognathic surgical planning.
即使在通过双侧矢状劈开下颌支截骨术(BSSRO)矫正下颌偏斜后,面部不对称仍常常持续存在,因为用于不对称分析的参考面部矢状面通常在下颌颏点(Me)矫正之前设定。我们的目的是开发一种预测性和定量性的方法,以评估通过虚拟BSSRO进行中线矫正后下颌骨的真正不对称性,并通过评估术后改善情况来验证其可用性。
对2010年9月至2014年5月在中山大学附属口腔医院(中国)的单纯半侧下颌骨延长(HE)患者进行了一项回顾性队列研究。根据接受术前正畸治疗患者的CBCT图像重建下颌模型。在通过虚拟BSSRO使下颌去旋转并对齐中线后,将延长的半侧下颌骨沿面部矢状面进行虚拟镜像。计算残余不对称性,定义为镜像延长侧与正常侧的叠加和布尔运算,包括体积差异以及横向和垂直不对称差异的长度。为了进行更具体的评估,将半侧下颌骨的两侧分为联合部和双侧联合部(SP)、下颌体(MB)和下颌角(MA)区域。其他临床变量包括Me点偏差、牙中线和磨牙关系。还计算了术后半侧下颌骨两侧之间的体积差异测量值,以验证虚拟手术的可用性。进行配对t检验,P值设定为0.05。
本研究纳入45例患者。体积差异分别为407.8±64.8mm³、2139.1±72.5mm³和422.5±36.9mm³;残余平均横向差异分别为1.9mm、1.0mm和2.2mm;平均垂直差异分别为1.1mm、2.2mm和2.2mm(虚拟手术前)。术后体积测量显示双侧下颌区域之间无统计学差异。
Me点矫正后下颌不对称仍然存在。通过虚拟BSSRO进行Me点矫正和下颌去旋转后,对下颌残余不对称性进行三维定量,为双侧下颌结构的全面不对称评估建立了真正的参考镜像平面,从而为正颌外科手术规划提供准确指导。