多灶性运动神经病和肌萎缩侧索硬化症中周围神经MRI与超声的比较研究
Comparative study of peripheral nerve Mri and ultrasound in multifocal motor neuropathy and amyotrophic lateral sclerosis.
作者信息
Jongbloed Bas A, Haakma Wieke, Goedee H Stephan, Bos Jeroen W, Bos Clemens, Hendrikse Jeroen, Van Den Berg Leonard H, Van Der Pol W Ludo
机构信息
Brain Centre Rudolf Magnus, Department of Neurology and Neurosurgery, University Medical Centre Utrecht, Room F02.230, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Department of Radiology, University Medical Centre Utrecht, Utrecht, The Netherlands.
出版信息
Muscle Nerve. 2016 Dec;54(6):1133-1135. doi: 10.1002/mus.25391. Epub 2016 Oct 1.
INTRODUCTION
Differentiating multifocal motor neuropathy (MMN) from amyotrophic lateral sclerosis (ALS) is important, as MMN is a difficult, but treatable disorder.
METHODS
We studied peripheral nerve imaging techniques in differentiating MMN from ALS by measuring the cross-sectional area (CSA) of the median and ulnar nerves in the forearms using high resolution ultrasound (HRUS) and MRI.
RESULTS
HRUS CSA values of the median nerve in the forearm (P = 0.002) and the ulnar nerve distal to the sulcus (P = 0.009) were significantly enlarged in patients with MMN. There was a positive correlation between CSA as measured with HRUS and MRI (Spearman rho 0.60; P < 0.001).
CONCLUSIONS
Peripheral nerve imaging is a potentially powerful technique to distinguish MMN from ALS. Muscle Nerve, 2016 Muscle Nerve 54: 1133-1135, 2016.
引言
区分多灶性运动神经病（MMN）和肌萎缩侧索硬化症（ALS）很重要，因为MMN是一种难治但可治疗的疾病。
方法
我们通过使用高分辨率超声（HRUS）和MRI测量前臂正中神经和尺神经的横截面积（CSA），研究了外周神经成像技术在区分MMN和ALS中的作用。
结果
MMN患者前臂正中神经的HRUS CSA值（P = 0.002）和沟远端尺神经的HRUS CSA值（P = 0.009）显著增大。HRUS和MRI测量的CSA之间存在正相关（Spearman相关系数0.60；P < 0.001）。
结论
外周神经成像可能是区分MMN和ALS的有力技术。《肌肉与神经》，2016年 2016年《肌肉与神经》第54卷：1133 - 1135页 。
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