Gualandi Malvina, Simoni Marzia, Manzato Emilia, Scanelli Giovanni
Eating Disorder Centre, University Hospital "Sant'Anna", Ferrara, Italy.
CNR Institute of Clinical Physiology, Via Trieste 41, 56126, Pisa, Italy.
Eat Weight Disord. 2016 Dec;21(4):617-624. doi: 10.1007/s40519-016-0314-4. Epub 2016 Aug 29.
To compare the relative prevalence of eating disorders moving from DSM-IV to DSM-5, and to reassess the overall medical impairment in the revised diagnostic classes.
We applied DSM-5 to 206 patients (age 15-56 years) previously studied and classified according to DSM-IV. Medical impairment was classified as low, medium, or high, based on a cumulative score of clinical severity (SCS), computed as the sum of specific weights assigned to different pathological conditions and their ascertained prognostic impact.
Application of DSM-5 produced a decrease in Eating Disorders Not Otherwise Specified (EDNOS) by 17 %, an increase in anorexia (AN) by 14 % and bulimia (BN) by 2.4 %; 44.6 % of EDNOS migrated to AN, 8 % to BN, and 30.8 % was reclassified as Other Specified Feeding and Eating Disorders (OSFED). Mean SCS was higher in AN than in other diagnoses independent of classification. Differently from EDNOS, no high score was found in OSFED. BMI (OR 0.74, 95 % CI 0.56-0.98) and duration of amenorrhea >1 year (OR 6.63, 95 % CI 1.29-34.16) resulted significantly associated with the risk for medium-high SCS level in AN classified with DSM-5.
The results confirmed that DSM-5 reduces the number of EDNOS. DSM-5 seems to better represent the clinical picture in OSFED than in EDNOS. The clinical relevance of BMI and duration of amenorrhea should be considered even more now that they are no longer used as diagnostic hallmarks of AN.
比较从《精神疾病诊断与统计手册》第四版(DSM-IV)到第五版(DSM-5)饮食失调症的相对患病率,并重新评估修订后诊断类别中的总体医学损害程度。
我们将DSM-5应用于之前根据DSM-IV进行研究和分类的206名患者(年龄15 - 56岁)。根据临床严重程度累积评分(SCS)将医学损害分为低、中、高三个等级,SCS通过对不同病理状况赋予的特定权重及其确定的预后影响求和计算得出。
应用DSM-5后,未另行规定的饮食失调症(EDNOS)减少了17%,神经性厌食症(AN)增加了14%,神经性贪食症(BN)增加了2.4%;44.6%的EDNOS转变为AN,8%转变为BN,30.8%被重新分类为其他特定的进食和喂养障碍(OSFED)。无论分类如何,AN的平均SCS均高于其他诊断。与EDNOS不同,OSFED中未发现高分情况。体重指数(BMI,比值比[OR] 0.74,95%置信区间[CI] 0.56 - 0.98)和闭经持续时间>1年(OR 6.63,95% CI 1.29 - 34.16)与DSM-5分类的AN中高SCS水平风险显著相关。
结果证实DSM-5减少了EDNOS的数量。DSM-5似乎比EDNOS能更好地呈现OSFED的临床情况。鉴于BMI和闭经持续时间不再用作AN的诊断标志,现在应更加重视它们的临床相关性。