School of Psychology, Flinders University, Adelaide, South Australia, Australia.
Int J Eat Disord. 2014 Jul;47(5):524-33. doi: 10.1002/eat.22257. Epub 2014 Feb 25.
In the DSM-5 diagnostic criteria for eating disorders, two main groups appear, threshold eating disorders (TED; anorexia nervosa, bulimia nervosa, and binge eating disorder), and other specified feeding and eating disorders (OSFED). In addition to calculating prevalence of these two groups, we examined the degree to which they could be differentiated in terms of impairment and risk factors.
Adolescent female twins (N = 699) were interviewed with the Eating Disorder Examination on three occasions spanning 12.70-19.84 years of age. Assessments also included self-report measures related to impairment and risk.
Prevalence of DSM-5 ED in this adolescent population was 10.4%; 5.4% for TED and 5% for OSFED. Impairment levels did not distinguish TED and OSFED groups at any wave. Examination of latent risk factors showed TED and OSFED groups to share a common genetic basis; however, largely nonoverlapping unique environmental influences contributed to the two groups. Specific risk factors commonly differentiated the no ED and TED groups, but not OSFED.
The findings suggest that TED and OSFED groups cannot be discriminated by prevalence or impairment or genetic risk factors. It is anticipated that OSFED will possess limited clinical utility for adolescents. Future research should examine clinical cases of these two groups in terms of meaningful differences, and a research focus should be maintained on both groups. Further examination of specific environmental risk factors that may attenuate the level of symptoms between the two groups may provide useful information for prevention efforts.
在 DSM-5 进食障碍诊断标准中,出现了两个主要组别,即阈量型进食障碍(TED;神经性厌食症、神经性贪食症和暴食障碍)和其他特定的进食障碍(OSFED)。除了计算这两个组别的患病率外,我们还研究了它们在损伤和风险因素方面的可区分程度。
对 699 名青春期女性双胞胎进行了三次访谈,时间跨度为 12.70-19.84 岁,访谈采用进食障碍检查。评估还包括与损伤和风险相关的自我报告测量。
在这个青春期人群中,DSM-5 ED 的患病率为 10.4%;TED 为 5.4%,OSFED 为 5%。在任何一波中,损伤水平都无法区分 TED 和 OSFED 组。对潜在风险因素的研究表明,TED 和 OSFED 组具有共同的遗传基础;然而,很大程度上不重叠的独特环境影响促成了这两个组。特定的风险因素通常可以区分无 ED 和 TED 组,但不能区分 OSFED。
这些发现表明,TED 和 OSFED 组不能通过患病率、损伤或遗传风险因素来区分。预计 OSFED 对青少年的临床应用有限。未来的研究应该根据有意义的差异,检查这两个组的临床病例,同时应该保持对这两个组的研究重点。进一步研究可能减轻两组之间症状水平的特定环境风险因素,可能为预防工作提供有用的信息。