Sathyamurthy Anjana, Winn Jessica N, Ibdah Jamal A, Tahan Veysel
Anjana Sathyamurthy, Jessica N Winn, Jamal A Ibdah, Veysel Tahan, Division of Gastroenterology and Hepatology, University of Missouri, Columbia, MO 65201, United States.
World J Gastrointest Pathophysiol. 2016 Aug 15;7(3):296-9. doi: 10.4291/wjgp.v7.i3.296.
A Dieulafoy's lesion is a dilated, aberrant, submucosal vessel that erodes the overlying epithelium without evidence of a primary ulcer or erosion. It can be located anywhere in the gastrointestinal tract. We describe a case of massive gastrointestinal bleeding from Dieulafoy's lesions in the duodenum. Etiology and precipitating events of a Dieulafoy's lesion are not well known. Bleeding can range from being self-limited to massive life- threatening. Endoscopic hemostasis can be achieved with a combination of therapeutic modalities. The endoscopic management includes sclerosant injection, heater probe, laser therapy, electrocautery, cyanoacrylate glue, banding, and clipping. Endoscopic tattooing can be helpful to locate the lesion for further endoscopic re-treatment or intraoperative wedge resection. Therapeutic options for re-bleeding lesions comprise of repeated endoscopic hemostasis, angiographic embolization or surgical wedge resection of the lesions. We present a 63-year-old Caucasian male with active bleeding from the two small bowel Dieulafoy's lesions, which was successfully controlled with epinephrine injection and clip applications.
Dieulafoy病是一种扩张的、走行异常的黏膜下血管,其侵蚀上方的上皮组织,但无原发性溃疡或糜烂的证据。它可位于胃肠道的任何部位。我们描述了一例十二指肠Dieulafoy病导致大量胃肠道出血的病例。Dieulafoy病的病因和诱发因素尚不清楚。出血范围可从自限性到危及生命的大出血。通过多种治疗方式联合可实现内镜止血。内镜治疗包括硬化剂注射、热探头、激光治疗、电灼、氰基丙烯酸酯胶、套扎和夹闭。内镜下纹身有助于定位病变,以便进一步进行内镜再治疗或术中楔形切除。复发性出血病变的治疗选择包括重复内镜止血、血管造影栓塞或病变的手术楔形切除。我们报告一名63岁的白种男性,因两处小肠Dieulafoy病出现活动性出血,通过肾上腺素注射和夹闭成功控制了出血。