Burn Center, Red Cross Hospital, Beverwijk, The Netherlands ; Department of Plastic, Reconstructive and Hand Surgery, Red Cross Hospital, Beverwijk, The Netherlands ; Association of Dutch Burn Centers, Beverwijk, The Netherlands ; Department of Plastic, Reconstructive and Hand Surgery, MOVE Research Institute, VU University Medical Center, Amsterdam, The Netherlands.
Burn Center, Red Cross Hospital, Beverwijk, The Netherlands ; Association of Dutch Burn Centers, Beverwijk, The Netherlands ; Department of Plastic, Reconstructive and Hand Surgery, MOVE Research Institute, VU University Medical Center, Amsterdam, The Netherlands.
Burns Trauma. 2015 Sep 30;3:18. doi: 10.1186/s41038-015-0017-5. eCollection 2015.
Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions. This review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery, focusing on usage and clinical effectiveness. Not only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage.
如今,大多数严重烧伤的患者都能存活下来。这种演变伴随着覆盖大面积烧伤的挑战。因此,越来越多的患者不得不应对烧伤疤痕的后遗症,并需要(多次)进行重建。本文综述了永久性烧伤创面覆盖和烧伤整形修复领域组织工程的发展,重点介绍了其使用和临床效果。本文不仅讨论了皮肤替代物,还讨论了皮下脂肪组织和软骨的替代物。