Department of Plastic and Reconstructive Surgery, Shaare-Zedek Medical Center, 12 Beith Street, Jerusalem, Israel.
Burns Trauma. 2016 Jul 4;4:12. doi: 10.1186/s41038-016-0037-9. eCollection 2016.
Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options. Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen. The dermal matrix serves as a scaffold for fibroblasts and endothelial cells. Vascularization of the matrix begins after 2-3 weeks, and eventually, the matrix incorporates with the tissue to create a new dermis. The main advantage of the Integra is that the neodermis is of the same quality as a native dermis.
In this case report, we present post-burn breast reconstruction of a 12-year-old girl using Integra, with a long follow-up of 7 years. To the best of our knowledge, there is no published follow-up of breast development after reconstruction with Integra from its beginning point at the age of puberty until after the growing process has terminated.
Integra is a reliable reconstructive tool for burned breast. If done before puberty, it can help in getting normal developing tissue with satisfying esthetic results of size, shape and symmetry.
儿童胸部全层烧伤是一个严重的问题，需要具有挑战性的重建选择。Integra 是一种由鲨鱼硫酸软骨素 6 硫酸盐和牛胶原蛋白组成的双层人工真皮。真皮基质可作为成纤维细胞和内皮细胞的支架。血管化始于 2-3 周后，最终基质与组织融合，形成新的真皮。Integra 的主要优点是新生真皮的质量与天然真皮相同。
在本病例报告中，我们介绍了使用 Integra 对 12 岁女孩进行烧伤后乳房重建的情况，随访时间长达 7 年。据我们所知，目前尚无 Integra 从青春期开始重建到生长过程结束后乳房发育的随访结果发表。
Integra 是烧伤乳房的可靠重建工具。如果在青春期前进行，它可以帮助获得正常发育的组织，并获得满意的大小、形状和对称性的美学效果。
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