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磁共振成像在诊断非酒精性脂肪性肝病合并严重肝脂肪变性的血色素沉着症中的应用价值

Usefulness of Magnetic Resonance Imaging for the Diagnosis of Hemochromatosis with Severe Hepatic Steatosis in Nonalcoholic Fatty Liver Disease.

作者信息

Nozaki Yuichi, Sato Noriko, Tajima Tsuyoshi, Hasuo Kanehiro, Kojima Yasushi, Umemoto Kumiko, Mishima Saori, Mikami Shintaro, Nakayama Tomohiro, Igari Toru, Akiyama Junichi, Imamura Masatoshi, Masaki Naohiko, Yanase Mikio

机构信息

Department of Gastroenterology, National Center for Global Health and Medicine, Japan.

出版信息

Intern Med. 2016;55(17):2413-7. doi: 10.2169/internalmedicine.55.6650. Epub 2016 Sep 1.

Abstract

The ratio of the number of patients with non-alcoholic steatohepatitis (NASH) to the total number of patients with liver dysfunction has increased in many countries around the world. Liver dysfunction is also caused by multiple blood transfusions in patients with leukemia and other hematological diseases, with liver dysfunction often accompanied by secondary hemochromatosis. This study describes a 25-year-old man with secondary hemochromatosis combined with NASH. Magnetic resonance imaging was useful for visualizing the distributions of both iron and fat in the liver of this patient in order to make a differential diagnosis and to evaluate the effect of treatment.

摘要

在世界上许多国家,非酒精性脂肪性肝炎(NASH)患者数量与肝功能不全患者总数的比例都有所上升。肝功能不全也可由白血病和其他血液系统疾病患者多次输血引起,肝功能不全常伴有继发性血色素沉着症。本研究描述了一名患有继发性血色素沉着症合并NASH的25岁男性。磁共振成像有助于观察该患者肝脏中铁和脂肪的分布情况,以便进行鉴别诊断和评估治疗效果。

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